Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50032768
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 160nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 160nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 700nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM81208(6-methoxy-N-(phenylmethyl)-1-propan-2-yl-benzimida...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM76780(SMR001395109 | MLS002471443 | cid_44143084 | 6-(1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50334335(2-(4-(benzylamino)-1-isopropyl-1H-benzo[d]imidazol...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50334334(cid_44143058 | CHEMBL1277149 | N-benzyl-1-isopropy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM81206(cid_44143057 | N-benzyl-6-ethoxy-1-propan-2-ylbenz...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50334336(2-(4-(Benzylamino)-1-isopropyl-1H-benzo[d]imidazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50334337(1-(4-(benzylamino)-1-isopropyl-1H-benzo[d]imidazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50334338(N-Benzyl-1-isopropyl-6-(2-methoxyethoxy)-1H-benzo[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50334339(cid_44143056 | CHEMBL1358008 | N-Benzyl-6-(1-(dime...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50334340(N-Benzyl-1-isopropyl-6-(piperidin-4-ylmethoxy)-1Hb...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM76779(cid_44143054 | MLS002471408 | N-benzyl-6-[(1-methy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50334341(cid_44143048 | CHEMBL1277150 | N-benzyl-6-butoxy-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed