Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50039368
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335908(tuberatolide B | CHEMBL1668774)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335909(2'-epi-Tuberatolide B | CHEMBL1668775)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335907(tuberatolide A | CHEMBL1668773)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335910(yezoquinolide | CHEMBL1668776)
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335911((R)-sargachromenol | CHEMBL1668777)
Affinity DataIC50: 9.00E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335912((S)-sargachromenol | CHEMBL1668778)
Affinity DataIC50: 1.70E+4nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226465(E-guggulsterone | pregna-4,17(20)-cis-diene-3,16-d...)
Affinity DataIC50: 4.40E+4nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed