Compile Data Set for Download or QSAR
Report error Found 134 Enz. Inhib. hit(s) with all data for entry = 50035884
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331888(5-Chloro-2-oxo-3-(thiophene-2-carbonyl)-2,3-dihydr...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012860(CHEMBL61422 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-acea...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012881(CHEMBL64404 | cid_74490 | 2-Methoxy-10H-phenothiaz...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012867(CHEMBL292324 | 1-Oxo-1,2-dihydro-6-thia-10b-aza-ac...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012846(CHEMBL64370 | 4,8-Difluoro-1-oxo-1,2-dihydro-6H-py...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012831(CHEMBL62772 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]a...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012831(CHEMBL62772 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]a...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012885(CHEMBL64858 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrol...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012883(CHEMBL293617 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-ace...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012835(CHEMBL62101 | 1-Oxo-1,2-dihydro-6-thia-10b-aza-ace...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012873(CHEMBL302879 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012841(CHEMBL64337 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]a...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012820(CHEMBL64763 | 4,8-Difluoro-1-oxo-1,2-dihydro-6H-py...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012827(10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE)
Affinity DataIC50: 320nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012827(10H-Phenoxazine | CHEMBL276850 | PHENOXAZINE)
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012869(CHEMBL62693 | 1-Oxo-1,2-dihydro-6-thia-10b-aza-ace...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012861(CHEMBL64051 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-d...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012856(CHEMBL60994 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]a...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012858(CHEMBL62616 | 1-Oxo-1,2-dihydro-6-thia-10b-aza-ace...)
Affinity DataIC50: 480nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012841(CHEMBL64337 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]a...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012839(CHEMBL61952 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-acea...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012873(CHEMBL302879 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012848(CHEMBL64422 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]a...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012877(CHEMBL63546 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrol...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012839(CHEMBL61952 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-acea...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012875(CHEMBL64490 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-acea...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012872(CHEMBL60136 | 1-Oxo-1,2-dihydro-6-thia-10b-aza-ace...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012820(CHEMBL64763 | 4,8-Difluoro-1-oxo-1,2-dihydro-6H-py...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012822(CHEMBL62572 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-acea...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012823(CHEMBL418665 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-ace...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012825(CHEMBL302838 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012870(CHEMBL64064 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-d...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012844(CHEMBL304698 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrro...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012885(CHEMBL64858 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrol...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012863(CHEMBL64396 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrol...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012865(CHEMBL64435 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-d...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012877(CHEMBL63546 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrol...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012856(CHEMBL60994 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]a...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012854(CHEMBL292884 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012872(CHEMBL60136 | 1-Oxo-1,2-dihydro-6-thia-10b-aza-ace...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012822(CHEMBL62572 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-acea...)
Affinity DataIC50: 900nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012846(CHEMBL64370 | 4,8-Difluoro-1-oxo-1,2-dihydro-6H-py...)
Affinity DataIC50: 900nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012855(phenothiazine | cid_7108 | dibenzo-1,4-thiazine | ...)
Affinity DataIC50: 940nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012849(CHEMBL304690 | 1-Oxo-1,2,6,7-tetrahydro-benzo[6,7]...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012869(CHEMBL62693 | 1-Oxo-1,2-dihydro-6-thia-10b-aza-ace...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012863(CHEMBL64396 | 8-Fluoro-1-oxo-1,2-dihydro-6H-pyrrol...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012882(CHEMBL62916 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-d...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012851(CHEMBL62617 | 1-Oxo-1,2-dihydro-6-thia-10b-aza-ace...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012878(CHEMBL444828 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012883(CHEMBL293617 | 1-Oxo-1,2-dihydro-6-oxa-10b-aza-ace...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
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