Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50039346
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335200(3-Benzyl-2-(2-bromo-3,4,5-trimethoxy-phenyl)-8-hyd...)
Affinity DataIC50: 5nMAssay Description:Inhibition of 17beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335199(3-Acetyl-7-(4-hydroxyphenyl)-2H-chromen-2-one | CH...)
Affinity DataIC50: 270nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by scintillation counting in presence of bacte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335195(3-Acetyl-2-oxo-2H-chromen-7-yl trifluoromethanesul...)
Affinity DataIC50: 360nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by scintillation counting in presence of bacte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335198(3-Acetyl-7-(4-methoxyphenyl)-2H-chromen-2-one | CH...)
Affinity DataIC50: 1.14E+3nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by scintillation counting in presence of bacte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335197(3-Acetyl-7-para-tolyl-2H-chromen-2-one | CHEMBL165...)
Affinity DataIC50: 1.24E+3nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by scintillation counting in presence of bacte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335196(3-Acetyl-7-phenyl-2H-chromen-2-one | CHEMBL1650699)
Affinity DataIC50: 1.93E+3nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by scintillation counting in presence of bacte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335199(3-Acetyl-7-(4-hydroxyphenyl)-2H-chromen-2-one | CH...)
Affinity DataKi:  143nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335195(3-Acetyl-2-oxo-2H-chromen-7-yl trifluoromethanesul...)
Affinity DataKi:  173nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335197(3-Acetyl-7-para-tolyl-2H-chromen-2-one | CHEMBL165...)
Affinity DataKi:  585nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335198(3-Acetyl-7-(4-methoxyphenyl)-2H-chromen-2-one | CH...)
Affinity DataKi:  585nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50335196(3-Acetyl-7-phenyl-2H-chromen-2-one | CHEMBL1650699)
Affinity DataKi:  911nMAssay Description:Displacement of [3H]estrone human recombinant 17beta-HSD1 expressed in Escherichia coli BL21 (DE3)-RIL by competitive inhibition assay in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed