Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50039352
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335260(N,N-dihexyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-2-...)
Affinity DataKi:  0.299nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335259(N,N-dibutyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-2-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM22038(2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexyl-2...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50060095(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335268(2-(2-(4-fluorophenyl)-1-methyl-1H-indol-3-yl)-N,N-...)
Affinity DataKi:  1.07nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50143220(N,N-dihexyl-2-oxo-2-(2-phenyl-1H-indol-3-yl)acetam...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335270(2-(1-methyl-2-(4-nitrophenyl)-1H-indol-3-yl)-2-oxo...)
Affinity DataKi:  1.57nMAssay Description:Displacement of [11C]PK11195 from high affinity binding site of TSPO in human brain membrane homogenate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335257(N-benzyl-2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N-me...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335270(2-(1-methyl-2-(4-nitrophenyl)-1H-indol-3-yl)-2-oxo...)
Affinity DataKi:  1.82nMAssay Description:Displacement of [11C]PK11195 from mixed affinity binding site of TSPO in human brain membrane homogenate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335262(N-benzyl-N-ethyl-2-(1-methyl-2-phenyl-1H-indol-3-y...)
Affinity DataKi:  2.92nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50143244(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-2-oxo-N,N-di...)
Affinity DataKi:  4.28nMAssay Description:Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335270(2-(1-methyl-2-(4-nitrophenyl)-1H-indol-3-yl)-2-oxo...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335269(N-benzyl-2-(2-(4-fluorophenyl)-1-methyl-1H-indol-3...)
Affinity DataKi:  6.77nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50143236(N,N-Dibutyl-2-oxo-2-(2-phenyl-1H-indol-3-yl)-aceta...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM22032(PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...)
Affinity DataKi:  9.30nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranslocator protein(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335270(2-(1-methyl-2-(4-nitrophenyl)-1H-indol-3-yl)-2-oxo...)
Affinity DataKi:  9.53nMAssay Description:Displacement of [11C]PK11195 from low affinity binding site of TSPO in human brain membrane homogenate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335256(N-benzyl-N-methyl-2-oxo-2-(2-phenyl-1H-indol-3-yl)...)
Affinity DataKi:  12nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50143223(2-oxo-2-(2-phenyl-1H-indol-3-yl)-N,N-dipropylaceta...)
Affinity DataKi:  12.2nMAssay Description:Displacement of [11C]PBR28 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335258(2-(1-methyl-2-phenyl-1H-indol-3-yl)-2-oxo-N,N-dipr...)
Affinity DataKi:  19.5nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335267(2-(2-(4-fluorophenyl)-1-methyl-1H-indol-3-yl)-2-ox...)
Affinity DataKi:  19.8nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335265(N-benzyl-N-methyl-2-(1-methyl-2-phenyl-1H-indol-3-...)
Affinity DataKi:  20.9nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM22040(Ro5-4864 | 4' Cl-diazepam | 4 -chlorodiazepam ...)
Affinity DataKi:  23nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335266(2-(5-fluoro-1-methyl-2-phenyl-1H-indol-3-yl)-2-oxo...)
Affinity DataKi:  23.7nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335264(N-methyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-2-oxo...)
Affinity DataKi:  38.2nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335261(N-butyl-N-ethyl-2-(1-methyl-2-phenyl-1H-indol-3-yl...)
Affinity DataKi:  60.2nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50335263(N-butyl-N-methyl-2-(1-methyl-2-phenyl-1H-indol-3-y...)
Affinity DataKi:  190nMAssay Description:Displacement of [11C]PK11195 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed