Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50032757
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334215BDBM50334215((+/-)-threo-3-Iodomethylphenidate | CHEMBL1641691)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50327148BDBM50327148((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50327148BDBM50327148((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334215BDBM50334215((+/-)-threo-3-Iodomethylphenidate | CHEMBL1641691)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062915BDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062915BDBM50062915(methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate | m...)
Affinity DataIC50: 156nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334214BDBM50334214((+/-)-threo-N-(p-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataKi:  363nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334212BDBM50334212((+/-)-threo-N-(o-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataKi:  517nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334211BDBM50334211((+/-)-threo-N-(p-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataKi:  658nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334209BDBM50334209((+/-)-threo-N-(o-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334212BDBM50334212((+/-)-threo-N-(o-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334211BDBM50334211((+/-)-threo-N-(p-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334210BDBM50334210((+/-)-threo-N-(m-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataKi:  2.06E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334209BDBM50334209((+/-)-threo-N-(o-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334213BDBM50334213((+/-)-threo-N-(m-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataKi:  2.75E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334214BDBM50334214((+/-)-threo-N-(p-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334210BDBM50334210((+/-)-threo-N-(m-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataIC50: 4.63E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334213BDBM50334213((+/-)-threo-N-(m-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataIC50: 7.97E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed