Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50032737
TargetMacrophage metalloelastase(Human)
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333940(4-((4-(4'-acetylbiphenyl-4-yl)-5-fluorothiophene-2...)
Affinity DataIC50: 7nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333942((R)-3-(5-fluoro-4-(4-(pyridin-4-yl)phenyl)thiophen...)
Affinity DataIC50: 13nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333941((R)-3-(4-(4'-acetylbiphenyl-4-yl)-5-fluorothiophen...)
Affinity DataIC50: 24nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333939((R)-N-(3-amino-3-oxo-1-phenylpropyl)-5-fluoro-4-(4...)
Affinity DataIC50: 85nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333937(trans-4-((5-fluoro-4-(4-(trifluoromethoxy)phenyl)t...)
Affinity DataIC50: 140nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333938((R)-3-(5-fluoro-4-(4-(trifluoromethoxy)phenyl)thio...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333934(trans-4-((4-(4-(trifluoromethoxy)phenyl)thiophene-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333935(trans-4-((3-(4-(trifluoromethoxy)phenyl)isothiazol...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Evotec Oai

Curated by ChEMBL
LigandPNGBDBM50333936(trans-4-((5-(4-(trifluoromethoxy)phenyl)isothiazol...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of MMP-12 catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed