Compile Data Set for Download or QSAR
Report error Found 154 Enz. Inhib. hit(s) with all data for entry = 50032790
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334773(trans-((2R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334787(cis-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50028094((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334770(cis-(2S,4S)-4-(3,4-dichlorophenyl)-N,N-dimethyl-1,...)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334764(trans-(2R,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,...)
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334768(trans-(2R,4S)-4-(3,4-dichlorophenyl)-N,N-dimethyl-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334766(cis-(2S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,...)
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334783(trans-(1S,2S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,...)
Affinity DataIC50: 8nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM22417(LY 94939 | Nisoxetine Inhibitor | Nisoxetine | LY1...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334775(trans-1-((2R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-te...)
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334787(cis-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334778(cis-1-((2R,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334772(cis-((2R,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334771(cis-(2R,4R)-4-(3,4-dichlorophenyl)-N,N-dimethyl-1,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334766(cis-(2S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
Sepracor

Curated by ChEMBL
LigandPNGBDBM82217([4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphth...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]norepinephrine reuptake at NET in rat brain synaptosome by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334777(cis-1-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 26nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334764(trans-(2R,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,...)
Affinity DataIC50: 27nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334787(cis-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50005548((+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquin...)
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334781(Cis-2-((2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334784(cis-(1S,2R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,...)
Affinity DataIC50: 33nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334775(trans-1-((2R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-te...)
Affinity DataIC50: 41nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334783(trans-(1S,2S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,...)
Affinity DataIC50: 42nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334766(cis-(2S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,...)
Affinity DataIC50: 45nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334773(trans-((2R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 45nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334760(trans-(2R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetra...)
Affinity DataIC50: 46nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334782(cis-2-((2R,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Sepracor

Curated by ChEMBL
LigandPNGBDBM82217([4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphth...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT in rat corpus striatum by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334776(trans-1-((2S,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-te...)
Affinity DataIC50: 54nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334785(trans-(1R,2R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,...)
Affinity DataIC50: 57nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Sepracor

Curated by ChEMBL
LigandPNGBDBM82217([4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphth...)
Affinity DataIC50: 60nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT in rat hypothalamus by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334774(trans-((2S,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 61nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334765(trans-(2S,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,...)
Affinity DataIC50: 62nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334764(trans-(2R,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,...)
Affinity DataIC50: 67nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334767((2R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)
Affinity DataIC50: 72nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334775(trans-1-((2R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-te...)
Affinity DataIC50: 72nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334767((2R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)
Affinity DataIC50: 73nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334782(cis-2-((2R,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 79nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334762(cis-(2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahy...)
Affinity DataIC50: 84nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334783(trans-(1S,2S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,...)
Affinity DataIC50: 91nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334773(trans-((2R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 92nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in MDCK cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50334774(trans-((2S,4R)-4-(3,4-dichlorophenyl)-1,2,3,4-tetr...)
Affinity DataIC50: 92nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in CHOK1 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
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