Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50041886
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50310150((S)-2-amino-4-(2,6-diethylpyridin-4-yl)-4-(3-(2-fl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303727((4R)-2-amino-4-(4-fluoro-3-(2-fluoropyridin-3-yl)p...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303717(rac-2-amino-4-(3-(2-fluoropyridin-3-yl)phenyl)-4-(...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50314604((+/-)-2-amino-4-(2',5'-difluorobiphenyl-3-yl)-1-me...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50417810(CHEMBL1651460)
Affinity DataIC50: 20nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303716(2-amino-4-(4-fluoro-3-(pyrimidin-5-yl)phenyl)-4-(4...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50314607(2-amino-4-(3'-methoxybiphenyl-3-yl)-1-methyl-4-(py...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50314603(2-amino-4-(3-(2-fluoropyridin-3-yl)phenyl)-1-methy...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50310158(rac-2-amino-4-(2-ethylpyridin-4-yl)-1-methyl-4-(3-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50310152(rac-2-amino-4-(2,6-diethylpyridin-4-yl)-1-methyl-4...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303739(2-amino-4-(4-methoxy-3-methylphenyl)-1-methyl-4-(3...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303750(2-amino-4-(3-chloro-4-methoxyphenyl)-1-methyl-4-(3...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50314611(2-amino-4-(2',3'-difluorobiphenyl-3-yl)-1-methyl-4...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303719(rac-2-amino-4-(4-methoxy-3-methylphenyl)-1-methyl-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50314609(3'-(2-amino-1-methyl-5-oxo-4-(pyridin-4-yl)-4,5-di...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303738(2-amino-4-(4-methoxy-3-(trifluoromethyl)phenyl)-1-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303752(2-amino-4-(3-butoxy-4-methoxyphenyl)-1-methyl-4-(3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303745(2-amino-4-(3-fluoro-4-methoxyphenyl)-1-methyl-4-(3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303749(2-amino-4-(3-ethoxy-4-methoxyphenyl)-1-methyl-4-(3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50314610(2-amino-4-(3'-fluorobiphenyl-3-yl)-1-methyl-4-(pyr...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303722(2-amino-4-(4-methoxy-3-propoxyphenyl)-1-methyl-4-(...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303723(2-amino-4-(3-isopropoxy-4-methoxyphenyl)-1-methyl-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50310155(rac-2-amino-1-methyl-4-(3-(pyridin-3-yl)phenyl)-4-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50314600(2-amino-4-(3',5'-difluorobiphenyl-3-yl)-1-methyl-4...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303757(2-amino-4-(3-(2-fluoropyridin-3-yl)phenyl)-1-methy...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50314612(2-amino-1-methyl-4-(3-(pyrazin-2-yl)phenyl)-4-(pyr...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50310159(rac-2-amino-4-(2-isopropylpyridin-4-yl)-1-methyl-4...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303744(2-amino-4-(3-(cyclopentyloxy)-4-methoxyphenyl)-1-m...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50310157(rac-2-amino-1-methyl-4-(2-methylpyridin-4-yl)-4-(3...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303751(2-amino-4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303733(2-amino-4-(3,4-dimethoxyphenyl)-1-methyl-4-(3-(pyr...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50310156(rac-2-amino-1-methyl-4-(2-methylpyridin-4-yl)-4-(3...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303724(2-amino-4-(3-cyclopentyl-4-methoxyphenyl)-1-methyl...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303758(2-amino-4-(2,3-dihydrobenzofuran-5-yl)-1-methyl-4-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303720(2-amino-4-(4-methoxy-3-methylphenyl)-1-methyl-4-(4...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50310149(2-amino-4-(biphenyl-3-yl)-1-methyl-4-(pyridin-4-yl...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50310151(rac-2-amino-4-(2,6-dimethylpyridin-4-yl)-1-methyl-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303736(5-(2-amino-1-methyl-5-oxo-4-(3-(pyridin-3-yl)pheny...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50310160(rac-2-amino-4-(2-ethyl-6-methylpyridin-4-yl)-1-met...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303742(5-Adamantan-1-yl-2-amino-5-(3,4-dimethoxy-phenyl)-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303748((S)-5-Adamantan-1-yl-2-amino-5-(4-methoxy-phenyl)-...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303721(5-Adamantan-1-yl-2-amino-5-(4-ethoxy-phenyl)-3-met...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303732(5-Adamantan-1-yl-2-amino-3-methyl-5-(4-trifluorome...)
Affinity DataIC50: 470nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303737(5-Adamantan-1-yl-2-amino-5-(4-butoxy-phenyl)-3-met...)
Affinity DataIC50: 871nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50303730(2-amino-4-(3-(6-methoxypyridin-3-yl)phenyl)-1-meth...)
Affinity DataIC50: 899nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50305477(6-(2-amino-4-cyclohexyl-5-oxo-4-phenyl-4,5-dihydro...)
Affinity DataIC50: 951nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50305467(2-amino-4-cyclohexyl-1-methyl-4-phenyl-1H-imidazol...)
Affinity DataIC50: 991nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50305481(2-amino-4-cyclohexyl-4-phenyl-1-((tetrahydrofuran-...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50305480(2-amino-4-cyclohexyl-1-(3,5-difluorobenzyl)-4-phen...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50305479(2-amino-1-benzyl-4-cyclohexyl-4-phenyl-1H-imidazol...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
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