Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 3583
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandPNGBDBM36514(CID46912122 | MDW933, 5)
Affinity DataKi:  7nM ΔG°:  -48.4kJ/mole IC50: 1.24nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandPNGBDBM36515(CID46912120 | MDW941, 6)
Affinity DataKi:  8nM ΔG°:  -48.1kJ/mole IC50: 1.94nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandPNGBDBM36513(CID46912128 | KY170, 4 | US9056847, Azido-cyclophe...)
Affinity DataKi:  44nM ΔG°:  -43.7kJ/mole IC50: 120nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandPNGBDBM36512(CID164227 | Cylcophellitol, 3 | US11826435, Compou...)
Affinity DataKi:  152nM ΔG°:  -40.5kJ/mole IC50: 150nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandPNGBDBM50078114((1S,2R,3S,4S,5R,6R)-7-Oxa-bicyclo[4.1.0]heptane-2,...)
Affinity DataKi:  5.30E+4nM ΔG°:  -25.4kJ/mole IC50: 9.49E+3nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed