Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50032676
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333096(CHEMBL1631924)
Affinity DataEC50:  14nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333103(CHEMBL1631931)
Affinity DataKd:  1.95nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333108(CHEMBL1631922)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333107(H-FGGFTGARKSARKAANQA-NH2 | CHEMBL1631921)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333106(H-FGGFTGK(Ac)RKSNRKK(Ac)ANQN-NH2 | CHEMBL1631920)
Affinity DataEC50:  355nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333105(H-FGGF(4-F)TGARKSARKLKNQ-NH2 | CHEMBL1631909)
Affinity DataEC50:  0.360nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50106479(FGGFTGARKSARK | H-FGGFTGARKSARK-NH2 | NC(1-13)NH2 ...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333104(H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2 | NC(1-17)NH2 ...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333098(CHEMBL1631926)
Affinity DataEC50:  1nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose in presence of compound 14 by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333098(CHEMBL1631926)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333097(CHEMBL1631925)
Affinity DataEC50:  30nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333095(CHEMBL1631923)
Affinity DataEC50:  0.610nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333103(CHEMBL1631931)
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333102(CHEMBL1631930)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333100(BzLGlyGGF(4-F)TGARKSARKLKNQ-NH2 | CHEMBL1631928)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333099(BzLGlyGGFTGARKSARKLKNQ-NH2 | CHEMBL1631927)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50417550(CHEMBL1631919)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50417551(CHEMBL1631932)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50417552(CHEMBL1631934)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50417553(CHEMBL1631933)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333101(BzLGlyGGFTGARKSARK-NH2 | CHEMBL1631929)
Affinity DataIC50: 755nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed