Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50032617
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331964(N-(1-Adamantyl)-7,7-dimethyl-5-phenyl-4,5,6,7-tetr...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331946(N-(1-Adamantyl)-5-phenyl-7-(trifluoromethyl)-4,5,6...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331960(N-(1-Adamantyl)-7-methyl-5-phenyl-4,5,6,7-tetrahyd...)
Affinity DataIC50: 76nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331947(1-Adamantyl-5-phenyl-7-(trifluoromethyl)-4,5,6,7-t...)
Affinity DataIC50: 97nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331951(N-(1-Adamantyl)-5-(2-chlorophenyl)-7-(trifluoromet...)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331952(N-(1-Adamantyl)-5-(3-chlorophenyl)-7-(trifluoromet...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331956(N-(1-Adamantyl)-5-(2-furanyl)-7-(trifluoromethyl)-...)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331965(N-(1-Adamantyl)-7,7-dimethyl-5-phenyl-4,7-dihydrop...)
Affinity DataIC50: 580nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331959(N-(1-Adamantyl)-5,7-diphenyl-4,5,6,7-tetrahydropyr...)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331963(N-(1-Adamantyl)-5-phenyl-4,5,6,7-tetrahydropyrazol...)
Affinity DataIC50: 5.30E+3nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331953(N-(1-Adamantyl)-5-(4-chlorophenyl)-7-(trifluoromet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331954(N-(1-Adamantyl)-5-(4-methoxyphenyl)-7-(trifluorome...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331955(N-(1-Adamantyl)-5-(4-ethyphenyl)-7-(trifluoromethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331950(N-{[5-Phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331957(N-(1-Adamantyl)-5-pyridin-3-yl-7-(trifluoromethyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331958(N-(1-Adamantyl)-5-tert-butyl-7-(trifluoromethyl)-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331949(N-[5-Phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331961(N-(1-Adamantyl)-5-methyl-7-phenyl-4,5,6,7-tetrahyd...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331962(N-(1-Adamantyl)-7-trifluoromethyl-4,5,6,7-tetrahyd...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331948(N-(1-Adamantyl)-4-methyl-7-trifluoromethyl-4,5,6,7...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50331966(N-(1-Adamantyl)-5-phenyl-7-(trifluoromethyl)pyrazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CaSR expressed in CHO cells assessed as [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed