Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50032611
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331873(5,6-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331879(5,6,7-trichloro-2-(trifluoromethyl)-2H-chromene-3-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331887((2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331881(6-chloro-2-(trifluoromethyl)-8-vinyl-2H-chromene-3...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331875(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331882(6-chloro-8-ethynyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331880(6,7,8-trichloro-2-(trifluoromethyl)-2H-chromene-3-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331874(6,7-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331877(5,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331883(6-chloro-8-phenyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331884(6-chloro-8-(phenylethynyl)-2-(trifluoromethyl)-2H-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331881(6-chloro-2-(trifluoromethyl)-8-vinyl-2H-chromene-3...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331049(6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxy...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331882(6-chloro-8-ethynyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331886(6-chloro-8-((4-sulfamoylphenyl)ethynyl)-2-(trifluo...)
Affinity DataIC50: 410nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331875(6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 740nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331885(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)
Affinity DataIC50: 760nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331879(5,6,7-trichloro-2-(trifluoromethyl)-2H-chromene-3-...)
Affinity DataIC50: 880nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331873(5,6-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331885(6-chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)...)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331880(6,7,8-trichloro-2-(trifluoromethyl)-2H-chromene-3-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331883(6-chloro-8-phenyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331877(5,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331876(5,7-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331886(6-chloro-8-((4-sulfamoylphenyl)ethynyl)-2-(trifluo...)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331049(6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxy...)
Affinity DataIC50: 2.92E+4nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331884(6-chloro-8-(phenylethynyl)-2-(trifluoromethyl)-2H-...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331874(6,7-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 9.45E+4nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331876(5,7-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331878(7,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331878(7,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed