Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50032597
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331722(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-phenylcyclohexyl)p...)
Affinity DataIC50: 0.950nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331727(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hydroxy-4-p-tolylc...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331723(N-(2-oxo-2-((3S,4S)-1-(cis-4-phenylcyclohexyl)-4-p...)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331722(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-phenylcyclohexyl)p...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331723(N-(2-oxo-2-((3S,4S)-1-(cis-4-phenylcyclohexyl)-4-p...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331727(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hydroxy-4-p-tolylc...)
Affinity DataIC50: 2.10nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331726(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hydroxy-4-phenylcy...)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331727(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hydroxy-4-p-tolylc...)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331723(N-(2-oxo-2-((3S,4S)-1-(cis-4-phenylcyclohexyl)-4-p...)
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331726(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hydroxy-4-phenylcy...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(N-(2-((3S,4S)-1-(cis-4-(benzo[d][1,3]dioxol-5-yl)-...)
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(N-(2-((3S,4S)-1-(cis-4-(benzo[d][1,3]dioxol-5-yl)-...)
Affinity DataIC50: 5.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331722(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-phenylcyclohexyl)p...)
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331715(N-(2-((3S,4S)-4-hydroxy-1-(cis-4-phenylcyclohexyl)...)
Affinity DataIC50: 7.40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(N-(2-((3S,4S)-1-(cis-4-(benzo[d][1,3]dioxol-5-yl)-...)
Affinity DataIC50: 7.80nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(N-(2-((3S,4S)-1-(cis-4-(benzo[d][1,3]dioxol-5-yl)-...)
Affinity DataIC50: 9.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331726(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hydroxy-4-phenylcy...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331715(N-(2-((3S,4S)-4-hydroxy-1-(cis-4-phenylcyclohexyl)...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331727(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hydroxy-4-p-tolylc...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331722(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-phenylcyclohexyl)p...)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331725(N-(2-((3S,4S)-4-(benzyloxy)-1-(cis-4-phenylcyclohe...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331724(N-(2-((3S,4S)-4-butoxy-1-(cis-4-phenylcyclohexyl)p...)
Affinity DataIC50: 47nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331725(N-(2-((3S,4S)-4-(benzyloxy)-1-(cis-4-phenylcyclohe...)
Affinity DataIC50: 51nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331724(N-(2-((3S,4S)-4-butoxy-1-(cis-4-phenylcyclohexyl)p...)
Affinity DataIC50: 54nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331719(N-(2-((3S,4S)-4-hydroxy-1-(cis-3-phenylcyclopentyl...)
Affinity DataIC50: 120nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331723(N-(2-oxo-2-((3S,4S)-1-(cis-4-phenylcyclohexyl)-4-p...)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331715(N-(2-((3S,4S)-4-hydroxy-1-(cis-4-phenylcyclohexyl)...)
Affinity DataIC50: 186nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331715(N-(2-((3S,4S)-4-hydroxy-1-(cis-4-phenylcyclohexyl)...)
Affinity DataIC50: 265nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331726(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hydroxy-4-phenylcy...)
Affinity DataIC50: 444nMAssay Description:Antagonist activity at mouse CCR2 assessed as inhibition of MCP1 induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331721(N-(2-((3S,4S)-4-hydroxy-1-(1-phenylpiperidin-4-yl)...)
Affinity DataIC50: 649nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(N-(2-((3S,4S)-1-(cis-4-(benzo[d][1,3]dioxol-5-yl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse CCR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331722(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-phenylcyclohexyl)p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331715(N-(2-((3S,4S)-4-hydroxy-1-(cis-4-phenylcyclohexyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331716(N-(2-((3S,4S)-4-hydroxy-1-(trans-3-phenylcyclohexy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331717(N-(2-((3S,4S)-4-hydroxy-1-(cis-3-phenylcyclohexyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331718(N-(2-((3S,4S)-4-hydroxy-1-(trans-3-phenylcyclopent...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331720(N-(2-((3S,4S)-4-hydroxy-1-(trans-4-phenylcyclohexy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Mouse)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(N-(2-((3S,4S)-1-(cis-4-(benzo[d][1,3]dioxol-5-yl)-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Rat)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(N-(2-((3S,4S)-1-(cis-4-(benzo[d][1,3]dioxol-5-yl)-...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of rat CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331727(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hydroxy-4-p-tolylc...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331728(N-(2-((3S,4S)-1-(cis-4-(benzo[d][1,3]dioxol-5-yl)-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCCR2 protein(Crab-eating macaque)
Incyte

Curated by ChEMBL
LigandPNGBDBM50331728(N-(2-((3S,4S)-1-(cis-4-(benzo[d][1,3]dioxol-5-yl)-...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of cynomolgus CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331726(N-(2-((3S,4S)-4-ethoxy-1-(cis-4-hydroxy-4-phenylcy...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed