Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50032592
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331659(N-tert-butyl-4-chloro-5-(4-(2-(4-(3-(4-cyanobenzyl...)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331659(N-tert-butyl-4-chloro-5-(4-(2-(4-(3-(4-cyanobenzyl...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331658(N-tert-butyl-5-(4-(2-(4-(1-butyl-3-(4-cyanobenzyl)...)
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331651(N-allyl-N-(1-(2-(1-(5-(N-tert-butylsulfamoyl)-2-ch...)
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331646(5-(4-(2-(4-(1-allyl-3-(4-cyanobenzyl)ureido)piperi...)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331646(5-(4-(2-(4-(1-allyl-3-(4-cyanobenzyl)ureido)piperi...)
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331639(4-cyanobenzyl allyl(1-(2-(1-(5-(N-tert-butylsulfam...)
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331638(4-(methylsulfonyl)benzyl allyl(1-(2-(1-(5-(N-tert-...)
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331642(5-(4-(2-(4-(1-allyl-3-(4-(trifluoromethyl)benzyl)u...)
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331660(4-nitrobenzyl allyl(1-(2-(1-(5-(N-tert-butylsulfam...)
Affinity DataIC50: 8.60nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331658(N-tert-butyl-5-(4-(2-(4-(1-butyl-3-(4-cyanobenzyl)...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331647(5-(4-(2-(4-(1-allyl-3-(4-(methylsulfonyl)phenyl)ur...)
Affinity DataIC50: 11.5nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331661(4-(trifluoromethyl)benzyl allyl(1-(2-(1-(5-(N-tert...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331638(4-(methylsulfonyl)benzyl allyl(1-(2-(1-(5-(N-tert-...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331654(N-allyl-N-(1-(2-(1-(5-(N-tert-butylsulfamoyl)-2-ch...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331645(5-(4-(2-(4-(1-allyl-3-(4-cyanophenyl)ureido)piperi...)
Affinity DataIC50: 20.5nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331662(4-fluorobenzyl allyl(1-(2-(1-(5-(N-tert-butylsulfa...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331660(4-nitrobenzyl allyl(1-(2-(1-(5-(N-tert-butylsulfam...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331645(5-(4-(2-(4-(1-allyl-3-(4-cyanophenyl)ureido)piperi...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331648(methyl 4-((3-allyl-3-(1-(2-(1-(5-(N-tert-butylsulf...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331640(4-(trifluoromethoxy)benzyl allyl(1-(2-(1-(5-(N-ter...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331643(5-(4-(2-(4-(1-allyl-3-(4-fluorophenyl)ureido)piper...)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331647(5-(4-(2-(4-(1-allyl-3-(4-(methylsulfonyl)phenyl)ur...)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331661(4-(trifluoromethyl)benzyl allyl(1-(2-(1-(5-(N-tert...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331663(methyl 4-((allyl(1-(2-(1-(5-(N-tert-butylsulfamoyl...)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331642(5-(4-(2-(4-(1-allyl-3-(4-(trifluoromethyl)benzyl)u...)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331644(5-(4-(2-(4-(1-allyl-3-(4-fluorobenzyl)ureido)piper...)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331652(N-allyl-N-(1-(2-(1-(5-(N-tert-butylsulfamoyl)-2-ch...)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331651(N-allyl-N-(1-(2-(1-(5-(N-tert-butylsulfamoyl)-2-ch...)
Affinity DataIC50: 53nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331650(4-(3-allyl-3-(1-(2-(1-(5-(N-tert-butylsulfamoyl)-2...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331641(5-(4-(2-(4-(1-allyl-3-(4-(trifluoromethyl)phenyl)u...)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331653(N-allyl-N-(1-(2-(1-(5-(N-tert-butylsulfamoyl)-2-ch...)
Affinity DataIC50: 65nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331654(N-allyl-N-(1-(2-(1-(5-(N-tert-butylsulfamoyl)-2-ch...)
Affinity DataIC50: 87nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331648(methyl 4-((3-allyl-3-(1-(2-(1-(5-(N-tert-butylsulf...)
Affinity DataIC50: 146nMAssay Description:Antagonist activity at CCR5 in human peripheral blood lymphocytes cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331657(N-allyl-N-(1-(2-(1-(2-chloro-4-fluoro-5-(N-methyls...)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331655(4-(2-(allyl(1-(2-(1-(5-(N-tert-butylsulfamoyl)-2-c...)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331656(N-allyl-N-(1-(2-(1-(2-chloro-4-fluoro-5-(N-methyls...)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331649(4-((3-allyl-3-(1-(2-(1-(5-(N-tert-butylsulfamoyl)-...)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at CCR5 in HOS cells assessed as inhibition of HIV-1 Ba-L infectionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed