Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50032585
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132069(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human dopamine receptor D2long expressed in CHO10001 cells assessed as stimulation of incorporation [3H]-thymidine incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132069(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Affinity DataEC50:  3.90nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in CHO dhfr-negative cells assessed as stimulation of [3H]-thymidine incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50331552([11C]-(+)-(4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexah...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132057(CHEMBL126128 | CHEMBL1180430 | N-{4-[4-(2-Methoxy-...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132069(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132047(CHEMBL126725 | CHEMBL1180455 | 3-(4-Chloro-phenyl)...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50331549([11C]-3-(2-oxo-3-(2-(4-(trifluoromethyl)piperidin-...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50331552([11C]-(+)-(4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexah...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity to human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132057(CHEMBL126128 | CHEMBL1180430 | N-{4-[4-(2-Methoxy-...)
Affinity DataKi:  13.5nMAssay Description:Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132069(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]spiperone from human dopamine D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132047(CHEMBL126725 | CHEMBL1180455 | 3-(4-Chloro-phenyl)...)
Affinity DataKi:  22.6nMAssay Description:Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132069(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50331549([11C]-3-(2-oxo-3-(2-(4-(trifluoromethyl)piperidin-...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]spiperone from human dopamine D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50331549([11C]-3-(2-oxo-3-(2-(4-(trifluoromethyl)piperidin-...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Pig)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50331549([11C]-3-(2-oxo-3-(2-(4-(trifluoromethyl)piperidin-...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]ketanserin from 5-HT2 receptor in porcine cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50331549([11C]-3-(2-oxo-3-(2-(4-(trifluoromethyl)piperidin-...)
Affinity DataKi:  270nMAssay Description:Displacement of [3H]SCH 23990 from dopamine D1 receptor in porcine cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Pig)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132069(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]ketanserin from 5-HT2 receptor in porcine cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg

Curated by ChEMBL
LigandPNGBDBM50132069(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]SCH 23990 from dopamine D1 receptor in porcine cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed