Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50032560
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331026((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331029((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331031((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331028((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331029((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331023((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331023((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...)
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331026((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331024((Z)-2-(5-Chloro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331027((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331026((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331025((Z)-2-(5-Bromo-2-oxo-1,2-dihydro-indol-3-ylideneme...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331024((Z)-2-(5-Chloro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331025((Z)-2-(5-Bromo-2-oxo-1,2-dihydro-indol-3-ylideneme...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331027((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331023((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331030((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331031((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331031((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331023((Z)-2-(5-Fluoro-2-oxo-1,2-dihydroindol-3-ylideneme...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331029((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331032((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...)
Affinity DataIC50: 8nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331027((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331033((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...)
Affinity DataIC50: 9nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331024((Z)-2-(5-Chloro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331030((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331028((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331032((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331033((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331030((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331025((Z)-2-(5-Bromo-2-oxo-1,2-dihydro-indol-3-ylideneme...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331029((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...)
Affinity DataIC50: 19nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331028((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331032((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...)
Affinity DataIC50: 26nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331032((R,Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-yliden...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 35nMAssay Description:Inhibition of c-Kit after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331031((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 36nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331030((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...)
Affinity DataIC50: 90nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331033((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...)
Affinity DataIC50: 112nMAssay Description:Inhibition of human VEGFR2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 139nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331025((Z)-2-(5-Bromo-2-oxo-1,2-dihydro-indol-3-ylideneme...)
Affinity DataIC50: 150nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331033((Z)-5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2...)
Affinity DataIC50: 215nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331024((Z)-2-(5-Chloro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 410nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331026((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 410nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331028((Z)-2-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenem...)
Affinity DataIC50: 5.64E+3nMAssay Description:Inhibition of VEGFR2-induced cell proliferation in HUVEC after 72 hrs by sulforhodamine B methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed