Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50032541
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50176062(3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-...)
Affinity DataKd:  1.40nMAssay Description:Inhibition of human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataKd:  0.830nMAssay Description:Inhibition of human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50247054(GSK-189254 | 6-(3-cyclobutyl-2,3,4,5-tetrahydro-1H...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(N1-Methyl-N3-phenyl-N3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(N1-Methyl-N3-phenyl-N3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  0.720nMAssay Description:Displacement of [3H]N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330791(N-Methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataKi:  0.890nMAssay Description:Displacement of [3H]N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(N-Methyl-3-phenyl-3-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(N1-Methyl-N2-phenyl-N2-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330792(N-methyl-3-(naphthalen-1-yl)-3-phenylpropan-1-amin...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330791(N-Methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(N-Methyl-3-phenyl-3-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(N-Methyl-3-phenyl-3-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(N1-Methyl-N2-phenyl-N2-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330787(4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...)
Affinity DataKi:  7nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330787(4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330787(4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330791(N-Methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataKi:  20nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330787(4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330786(N-Methyl-3-phenyl-3-(6-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330791(N-Methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330790(N-Methyl-3-phenyl-3-(4-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(N1-Methyl-N3-phenyl-N3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(N1-Methyl-N2-phenyl-N2-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi: >70nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330788(N1-Methyl-N2-phenyl-N2-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330789(N1-Methyl-N3-phenyl-N3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330786(N-Methyl-3-phenyl-3-(6-(2-(pyrrolidin-1-yl)ethoxy)...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]N-R-methylhistamine from human H3 receptor isolated from C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]N-R-methylhistamine from rat H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed