Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50032463
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329674(2-[4-(2-Naphthalen)-phenyl]-4-methyl-octahydro-1,4...)
Affinity DataIC50: 800nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329672(2-[4-(6-Methoxy-2-naphthalen)-phenyl]-4-methyl-oct...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329673(2-[4-(2-Naphthalen)-phenyl]-4-methylmorpholin-2-ol...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329670(2-[4-(6-Methoxy-2-naphthalen)-phenyl]-4-methylmorp...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329669(2-(2-Naphthalene)-4-methyl-octahydro-1,4-benzoxazi...)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329671(3-[4-(6-Methoxy-2-naphthalen)-phenyl]-octahydro-1,...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329665(3-(6-Methoxy-2-naphthalene)-octahydro-1,4-pyrido[2...)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50213690(2-Biphenyl-4-yl-4-methyl-octahydro-benzo[1,4]oxazi...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329666(2-(6-Methoxy-2-naphthalene)-4-methyl-octahydro-1,4...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329668(3-(2-Naphthalene)-octahydro-1,4-pyrido[2,1-c]oxazi...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329667(2-(2-Naphthalene)-4-methylmorpholin-2-ol hydrobrom...)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50329664(2-(6-Methoxy-2-naphthalene)-4-methylmorpholin-2-ol...)
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed