Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50032447
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329397(N-(4-Ethylphenyl)-5-methylbenzo[d]oxazol-2-amine |...)
Affinity DataIC50: 120nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329394(5-Chloro-N-(4-ethylphenyl)benzo[d]oxazol-2-amine |...)
Affinity DataIC50: 950nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329392(N-(4-Ethylphenyl)benzo[d]oxazol-2-amine | CHEMBL12...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329404(N-(3-Bromophenyl)-5-methoxybenzo[d]oxazol-2-amine ...)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329402(N-(4-Isopropylphenyl)-5-methoxybenzo[d]oxazol-2-am...)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329403(5-Methoxy-N-(4-(methylthio)phenyl)benzo[d]oxazol-2...)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329393(5-Chloro-N-phenylbenzo[d]oxazol-2-amine | CHEMBL12...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329396(5-Methyl-N-phenylbenzo[d]oxazol-2-amine | CHEMBL12...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329398(N-(2-Ethylphenyl)-5-methylbenzo[d]oxazol-2-amine |...)
Affinity DataIC50: 5.66E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329400(N-(3-Methoxyphenyl)-5-methylbenzo[d]oxazol-2-amine...)
Affinity DataIC50: 6.83E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329399(6-Methyl-N-(4-(methylthio)phenyl)benzo[d]oxazol-2-...)
Affinity DataIC50: 7.31E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329401(5-Methoxy-N-phenylbenzo[d]oxazol-2-amine | CHEMBL1...)
Affinity DataIC50: 7.88E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM49481(MLS000564967 | SMR000152172 | N-phenyl-1,3-benzoxa...)
Affinity DataIC50: 8.91E+3nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50329395(N-(4-Ethylphenyl)-5-nitrobenzo[d]oxazol-2-amine | ...)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of 5-lipoxygenase in BALB/c mouse BMMC assessed as LTC4 release after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed