Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50032521
TargetGlutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50330415((R)-N-(2-(4'-(2-(methylsulfonamido)ethyl)biphenyl-...)
Affinity DataEC50:  150nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50094024(propane-2-sulfonic acid [2-(4'-cyano-biphenyl-4-yl...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at GluR2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50112770((R,R) Propane-2-sulfonic acid [2-(4-iodo-phenyl)-c...)
Affinity DataEC50:  230nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50094024(propane-2-sulfonic acid [2-(4'-cyano-biphenyl-4-yl...)
Affinity DataEC50:  290nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50102263(N-{4-[1-Methyl-2-(propane-2-sulfonylamino)-ethyl]-...)
Affinity DataEC50:  520nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50112771((+/-) Propane-2-sulfonic acid [2-(4-bromo-phenyl)-...)
Affinity DataEC50:  520nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50102263(N-{4-[1-Methyl-2-(propane-2-sulfonylamino)-ethyl]-...)
Affinity DataEC50:  520nMAssay Description:Agonist activity at GluR2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50112771((+/-) Propane-2-sulfonic acid [2-(4-bromo-phenyl)-...)
Affinity DataEC50:  520nMAssay Description:Agonist activity at GluR2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50330419(N,N'-(nonane-1,9-diyl)dipropane-2-sulfonamide | CH...)
Affinity DataEC50:  660nMAssay Description:Inhibition of GluR1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 4(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50330416(N-{(R)-2-[4'-((S)-2-Methanesulfonylamino-1-methyl-...)
Affinity DataEC50:  870nMAssay Description:Inhibition of rat recombinant GluR4 in cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50330417(N,N'-(octane-1,8-diyl)dipropane-2-sulfonamide | CH...)
Affinity DataEC50:  910nMAssay Description:Inhibition of GluR1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50330414(N-(2-(4-tert-butylphenyl)propyl)methanesulfonamide...)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50094024(propane-2-sulfonic acid [2-(4'-cyano-biphenyl-4-yl...)
Affinity DataEC50:  1.44E+3nMAssay Description:Inhibition of GluR2 flop expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50330420(N-((3S,4S)-1-methyl-4-(4'-(N-methylmethylsulfonami...)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of human recombinant GluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50094024(propane-2-sulfonic acid [2-(4'-cyano-biphenyl-4-yl...)
Affinity DataEC50:  1.66E+3nMAssay Description:Inhibition of GluR3 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323793(N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-in...)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of human recombinant GluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50330418(N,N'-(heptane-1,7-diyl)dipropane-2-sulfonamide | C...)
Affinity DataEC50:  2.88E+3nMAssay Description:Inhibition of GluR1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50094018(N-[2-(4-Thiophen-3-yl-phenyl)-propyl]-methanesulfo...)
Affinity DataEC50:  4.50E+3nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50094024(propane-2-sulfonic acid [2-(4'-cyano-biphenyl-4-yl...)
Affinity DataEC50:  5.65E+3nMAssay Description:Inhibition of GluR1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50330421(N-(5-(thiophen-3-yl)-2,3-dihydro-1H-inden-2-yl)pro...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of human recombinant GluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50094008(N-[2-(2'-Fluoro-biphenyl-4-yl)-propyl]-methanesulf...)
Affinity DataEC50:  1.96E+4nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50330411(1,2,3,7,8,11a-Hexahydro-6,9,11-trioxa-3a-aza-cyclo...)
Affinity DataEC50:  2.10E+4nMAssay Description:Inhibition of GluR1 expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50094009(Piperidin-1-yl-quinoxalin-6-yl-methanone | CX-516 ...)
Affinity DataEC50:  1.56E+5nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50094009(Piperidin-1-yl-quinoxalin-6-yl-methanone | CX-516 ...)
Affinity DataEC50: >1.00E+6nMAssay Description:Inhibition of GluR4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50330413((R)-N-(2-phenylpropyl)methanesulfonamide | CHEMBL1...)
Affinity DataEC50:  1.98E+6nMAssay Description:Inhibition of GluR2 flop expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed