Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50032373
TargetEpidermal growth factor receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327948(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of EGFR phosphorylation in human MIAPaCa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327947(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of EGFR phosphorylation in human MIAPaCa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327950(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327947(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327948(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327959(trans-N-(4-(4-amino-1-(4-(4-isopropylpiperazin-1-y...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327948(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 12.5nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327952(N-(4-(4-amino-1-(1'-(3-methoxypropyl)-1,4'-bipiper...)
Affinity DataIC50: 13.8nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327954(N-(4-(4-amino-1-(1'-methyl-1,4'-bipiperidin-4-yl)-...)
Affinity DataIC50: 14.5nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327953(N-(4-(4-amino-1-(1'-isopropyl-1,4'-bipiperidin-4-y...)
Affinity DataIC50: 15.1nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327950(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 15.4nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327947(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 16nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327955(trans-2-(4-(4-(4-amino-3-(4-(7-chlorobenzo[d]oxazo...)
Affinity DataIC50: 21.5nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327957(trans-N-(4-(4-amino-1-(4-(4-(3-methoxypropyl)piper...)
Affinity DataIC50: 21.5nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327949(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 22nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327951(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 29nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327960(trans-N-(4-(4-amino-1-(4-morpholinocyclohexyl)-1H-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327959(trans-N-(4-(4-amino-1-(4-(4-isopropylpiperazin-1-y...)
Affinity DataIC50: 45.1nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327951(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 49nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 51nMAssay Description:Inhibition of EGFR phosphorylation in human MIAPaCa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327958(cis-N-(4-(4-amino-1-(4-(4-isopropylpiperazin-1-yl)...)
Affinity DataIC50: 62nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50219382(3-((1s,3s)-3-(4-methylpiperazin-1-yl)cyclobutyl)-1...)
Affinity DataIC50: 65nMAssay Description:Inhibition of IGF1R phosphorylation in human MIAPaCa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327962(cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyc...)
Affinity DataIC50: 72nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327957(trans-N-(4-(4-amino-1-(4-(4-(3-methoxypropyl)piper...)
Affinity DataIC50: 72.4nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327963(cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyc...)
Affinity DataIC50: 77nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327947(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 87nMAssay Description:Inhibition of IGF1R phosphorylation in human MIAPaCa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327964(N-(4-(4-amino-7-((1s,4s)-4-(4-methylpiperazin-1-yl...)
Affinity DataIC50: 94nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327954(N-(4-(4-amino-1-(1'-methyl-1,4'-bipiperidin-4-yl)-...)
Affinity DataIC50: 108nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327970(cis-2-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyc...)
Affinity DataIC50: 113nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327953(N-(4-(4-amino-1-(1'-isopropyl-1,4'-bipiperidin-4-y...)
Affinity DataIC50: 115nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327955(trans-2-(4-(4-(4-amino-3-(4-(7-chlorobenzo[d]oxazo...)
Affinity DataIC50: 126nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 140nMAssay Description:Inhibition of ERBb2 phosphorylation in human MIAPaCa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327965(cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyc...)
Affinity DataIC50: 160nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327958(cis-N-(4-(4-amino-1-(4-(4-isopropylpiperazin-1-yl)...)
Affinity DataIC50: 174nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327969(cis-methyl 2-(4-(4-amino-1-(4-(4-methylpiperazin-1...)
Affinity DataIC50: 179nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327966(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 196nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327963(cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyc...)
Affinity DataIC50: 200nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327948(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 207nMAssay Description:Inhibition of IGF1R phosphorylation in human MIAPaCa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327952(N-(4-(4-amino-1-(1'-(3-methoxypropyl)-1,4'-bipiper...)
Affinity DataIC50: 283nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327960(trans-N-(4-(4-amino-1-(4-morpholinocyclohexyl)-1H-...)
Affinity DataIC50: 334nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327948(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 340nMAssay Description:Inhibition of ERBb2 phosphorylation in human MIAPaCa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327961(cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyc...)
Affinity DataIC50: 348nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327947(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 362nMAssay Description:Inhibition of ERBb2 phosphorylation in human MIAPaCa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327956(cis-N-(4-(4-amino-1-(4-(4-(3-methoxypropyl)piperaz...)
Affinity DataIC50: 397nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327968(cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyc...)
Affinity DataIC50: 415nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327956(cis-N-(4-(4-amino-1-(4-(4-(3-methoxypropyl)piperaz...)
Affinity DataIC50: 424nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 433nMAssay Description:Inhibition of EGFR phosphorylation in human MIAPaCa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327949(trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)c...)
Affinity DataIC50: 478nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327967(cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyc...)
Affinity DataIC50: 584nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327971(cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyc...)
Affinity DataIC50: 810nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
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