Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50039274
TargetSodium-dependent serotonin transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataIC50: 12.6nMAssay Description:Displacement of [3H]paroxetine from SERT in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325937(rac-N-methyl-3-(naphthalen-2-yl)-3-(2H-tetrazol-2-...)
Affinity DataIC50: 13.3nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325936((S)-3-(5-(2H-1,2,3-triazol-2-yl)-2H-tetrazol-2-yl)...)
Affinity DataIC50: 14.7nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325933((S)-3-(3,4-dichlorophenyl)-N-methyl-3-(5-methyl-2H...)
Affinity DataIC50: 19.8nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325937(rac-N-methyl-3-(naphthalen-2-yl)-3-(2H-tetrazol-2-...)
Affinity DataIC50: 32nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325933((S)-3-(3,4-dichlorophenyl)-N-methyl-3-(5-methyl-2H...)
Affinity DataIC50: 58nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325935(rac-3-(3,4-dichlorophenyl)-N-methyl-3-(2H-tetrazol...)
Affinity DataIC50: 69nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50: 72.4nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325934(rac-3-(3,4-dichlorophenyl)-N,N-dimethyl-3-(2H-tetr...)
Affinity DataIC50: 78nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325936((S)-3-(5-(2H-1,2,3-triazol-2-yl)-2H-tetrazol-2-yl)...)
Affinity DataIC50: 91.7nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50: 93.8nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325935(rac-3-(3,4-dichlorophenyl)-N-methyl-3-(2H-tetrazol...)
Affinity DataIC50: 116nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325932(rac-N,N-dimethyl-3-(naphthalen-2-yl)-3-(2H-tetrazo...)
Affinity DataIC50: 138nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325933((S)-3-(3,4-dichlorophenyl)-N-methyl-3-(5-methyl-2H...)
Affinity DataIC50: 143nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325935(rac-3-(3,4-dichlorophenyl)-N-methyl-3-(2H-tetrazol...)
Affinity DataIC50: 181nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)
Affinity DataIC50: 215nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325934(rac-3-(3,4-dichlorophenyl)-N,N-dimethyl-3-(2H-tetr...)
Affinity DataIC50: 234nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325932(rac-N,N-dimethyl-3-(naphthalen-2-yl)-3-(2H-tetrazo...)
Affinity DataIC50: 264nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325934(rac-3-(3,4-dichlorophenyl)-N,N-dimethyl-3-(2H-tetr...)
Affinity DataIC50: 279nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataIC50: 581nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325932(rac-N,N-dimethyl-3-(naphthalen-2-yl)-3-(2H-tetrazo...)
Affinity DataIC50: 616nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325936((S)-3-(5-(2H-1,2,3-triazol-2-yl)-2H-tetrazol-2-yl)...)
Affinity DataIC50: 660nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325937(rac-N-methyl-3-(naphthalen-2-yl)-3-(2H-tetrazol-2-...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325933((S)-3-(3,4-dichlorophenyl)-N-methyl-3-(5-methyl-2H...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataIC50: 7.34E+3nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325933((S)-3-(3,4-dichlorophenyl)-N-methyl-3-(5-methyl-2H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325933((S)-3-(3,4-dichlorophenyl)-N-methyl-3-(5-methyl-2H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325933((S)-3-(3,4-dichlorophenyl)-N-methyl-3-(5-methyl-2H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50325933((S)-3-(3,4-dichlorophenyl)-N-methyl-3-(5-methyl-2H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed