Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50032253
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326249(ethyl 5-(dimethylcarbamoyloxy)-1-methyl-1,4-dihydr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326250((3aR,9bS)-1-methyl-1,2,3,3a,4,9b-hexahydrothiochro...)
Affinity DataIC50: 8.11nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10961(homotolserine | eseroline 2-ethylphenylcarbamate |...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10973((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326251((3aR,9bS)-1-methyl-2,3,3a,4,5,9b-hexahydro-1H-benz...)
Affinity DataIC50: 17.3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10972((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10958((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 22.1nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10978((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326252((3aR,9bS)-1-methyl-1,2,3,3a,4,9b-hexahydrochromeno...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326253((R)-3-(1-(piperidin-1-yl)ethyl)phenyl dimethylcarb...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326248((3aS,8aS)-1,3a-dimethyl-1,2,3,3a,8,8a-hexahydropyr...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326247((3aS,8aS)-1,3a-dimethyl-1,2,3,3a,8,8a-hexahydropyr...)
Affinity DataIC50: 56.7nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 56.7nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10982(3,5-dimethylphenserine | (3aS,8aR)-1,3a,8-trimethy...)
Affinity DataIC50: 78nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326246((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50: 94nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50290389(Methyl-carbamic acid 1-(3-fluoro-pyridin-4-ylamino...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50292573((2-Ethyl-phenyl)-carbamic acid (3aS,8aS)-1,3a,8-tr...)
Affinity DataIC50: 125nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326265(quilostigmine | CHEMBL1243298)
Affinity DataIC50: 148nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326264((3aS,8aR)-8-benzyl-1,3a-dimethyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 161nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326263((3aS,8aR)-8-benzyl-1,3a-dimethyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 245nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10985((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50: 285nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326262((3aS,8aR)-8-formyl-1,3a-dimethyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326261(Ethyl-carbamic acid 1-methyl-8,10,12-trioxa-tricyc...)
Affinity DataIC50: 388nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10980((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 690nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10988((3aS,8aR)-6-[(dimethylamino)methyl]-1,3a,8-trimeth...)
Affinity DataIC50: 780nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326260((3aS,8aR)-3a-methyl-1,2,3,3a,8,8a-hexahydropyrrolo...)
Affinity DataIC50: 830nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50014112(CHEMBL74257 | Methyl-carbamic acid 1-benzyl-3a,8-d...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326259((3aS,8aR)-8-formyl-1,3a-dimethyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326258(2-Chlorophenylcarbamic Acid 1-Benzyl-1,2,3,4-tetra...)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326257((3aS,8aR)-1,8-dibenzyl-3a-methyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326256((4-Isopropyl-phenyl)-carbamic acid 1-methyl-8,10,1...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326255((3aR,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50: 9.89E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326254((3aS,8aR)-1,8-dibenzyl-3a-methyl-1,2,3,3a,8,8a-hex...)
Affinity DataIC50: 4.11E+4nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed