Compile Data Set for Download or QSAR
Report error Found 176 Enz. Inhib. hit(s) with all data for entry = 50039281
TargetMuscarinic acetylcholine receptor M3(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50122054(N-desmethyl-Clozapine | 8-Chloro-11-piperazin-1-yl...)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326218(N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)pr...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326219(CHEMBL1242950 | CHEMBL2206334 | 4-(4-butylpiperidi...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50122054(N-desmethyl-Clozapine | 8-Chloro-11-piperazin-1-yl...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50263887(1-(1'-2-methylbenzyl)-1,4'-bipiperidin-4-yl)-1H-be...)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326217(N-{1-[3-(6,7-Difluoro-2-oxo-3,4-dihydro-2H-quinoli...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326232(2-(3-Methoxy-phenyl)-N-{1-[3-(3-oxo-2,3-dihydro-be...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326233(N-{1-[3-(5-Fluoro-2-oxo-3,4-dihydro-2H-quinolin-1-...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326234(N-{1-[3-(6-Fluoro-2-oxo-3,4-dihydro-2H-quinolin-1-...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326235(N-{1-[3-(7-Fluoro-2-oxo-3,4-dihydro-2H-quinolin-1-...)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326236(N-{1-[3-(8-Fluoro-2-oxo-3,4-dihydro-2H-quinolin-1-...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326237(N-{1-[3-(6-Methoxy-2-oxo-3,4-dihydro-2H-quinolin-1...)
Affinity DataEC50:  560nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326238(N-{1-[3-(7-Methoxy-2-oxo-3,4-dihydro-2H-quinolin-1...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326239(N-{1-[3-(2-Oxo-3,4-dihydro-2H-quinolin-1-yl)-propy...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326240(N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1,4]thiazin-4-yl)...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326241(N-(1-(3-(2-oxobenzo[d]oxazol-3(2H)-yl)propyl)piper...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326242(N-Methyl-N-{1-[3-(3-oxo-2,3-dihydro-benzo[1,4]oxaz...)
Affinity DataEC50:  910nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326243(N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-...)
Affinity DataEC50:  970nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326244(N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-...)
Affinity DataEC50:  180nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326245(N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326220(N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-...)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326221(Cyclopropanecarboxylic acid{1-[3-(3-oxo-2,3-dihydr...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326222(Cyclobutanecarboxylic acid{1-[3-(3-oxo-2,3-dihydro...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326223(Cyclopentanecarboxylic acid{1-[3-(3-oxo-2,3-dihydr...)
Affinity DataEC50:  350nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326224(N-{1-[3-(5-Fluoro-2-oxo-3,4-dihydro-2H-quinolin-1-...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326225(N-{1-[3-(6-Fluoro-2-oxo-3,4-dihydro-2H-quinolin-1-...)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326226(N-{1-[3-(7-Fluoro-2-oxo-3,4-dihydro-2H-quinolin-1-...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326227(N-{1-[3-(8-Fluoro-2-oxo-3,4-dihydro-2H-quinolin-1-...)
Affinity DataEC50:  310nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326228(N-{1-[3-(6,7-Difluoro-2-oxo-3,4-dihydro-2H-quinoli...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326229(N-{1-[3-(6,7-Difluoro-2-oxo-3,4-dihydro-2H-quinoli...)
Affinity DataEC50:  86nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326230(N-{1-[3-(6,7-Difluoro-3-oxo-2,3-dihydro-benzo[1,4]...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human muscarinic M2 receptor expressed in CHO-K1 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMuscarinic acetylcholine receptor M3(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in BHK-21 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMuscarinic acetylcholine receptor M4(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataEC50:  6.20nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in BHK-21 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMuscarinic acetylcholine receptor M4(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50122054(N-desmethyl-Clozapine | 8-Chloro-11-piperazin-1-yl...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in BHK-21 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326217(N-{1-[3-(6,7-Difluoro-2-oxo-3,4-dihydro-2H-quinoli...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in BHK-21 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326217(N-{1-[3-(6,7-Difluoro-2-oxo-3,4-dihydro-2H-quinoli...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326231(N-{1-[3-(6,7-Difluoro-2-oxo-3,4-dihydro-2H-quinoli...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]-4-DAMP from human muscarinic M3 receptor expressed in BHK-21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-4-DAMP from human muscarinic M5 receptor expressed in BHK-21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-AFDX-384 from human muscarinic M2 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-4-DAMP from human muscarinic M4 receptor expressed in BHK-21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50003359(CHEMBL73149 | LY 246708 | CHEMBL21536 | 5-(4-Hexyl...)
Affinity DataKi:  13nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326219(CHEMBL1242950 | CHEMBL2206334 | 4-(4-butylpiperidi...)
Affinity DataKi:  18nMAssay Description:Binding affinity to human adrenergic alpha1A receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
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