Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50032073
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323919(4-(4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ur...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323917(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323918(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-me...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 10.8nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323922(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-methyl...)
Affinity DataIC50: 18.4nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323919(4-(4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ur...)
Affinity DataIC50: 62.6nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 76.2nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 83.4nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 84.8nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323921(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50: 92.3nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323921(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323922(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-methyl...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323918(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-me...)
Affinity DataIC50: 189nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 226nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323919(4-(4-(3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)ur...)
Affinity DataIC50: 237nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323921(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50: 244nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323918(1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-me...)
Affinity DataIC50: 414nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323920(N-methyl-4-(4-(3-(4-((4-methylpiperazin-1-yl)methy...)
Affinity DataIC50: 572nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323917(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-mor...)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323916(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(2-morphol...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323915(N-methyl-4-(4-(4-((4-methylpiperazin-1-yl)methyl)b...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mouse recombinant N-terminal His6-tagged Abl by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323920(N-methyl-4-(4-(3-(4-((4-methylpiperazin-1-yl)methy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323915(N-methyl-4-(4-(4-((4-methylpiperazin-1-yl)methyl)b...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323916(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(2-morphol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323916(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(2-morphol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323920(N-methyl-4-(4-(3-(4-((4-methylpiperazin-1-yl)methy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant full-length N-terminal GST-tagged p38alpha expressed in Escherichia coli by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50323915(N-methyl-4-(4-(4-((4-methylpiperazin-1-yl)methyl)b...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant full-length GST-tagged B-Raf by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed