Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 8126
TargetCytosol aminopeptidase [33-68,L62W](Pig)
Academy of Sciences of The Czech Republic

LigandPNGBDBM234297(Met-ψ[P(O)(OH)CH2]-Ala (5))
Affinity DataKi:  3.64E+3nM ΔG°:  -31.0kJ/molepH: 8.4 T: 2°CAssay Description:LAP was assayed in 75 mM triethanolamine hydrochloride buffer (pH = 8.4, containing 5 mM MgCl2) at 25°C. The substrate (L-leucine-p-nitroanilide) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytosol aminopeptidase [33-68,L62W](Pig)
Academy of Sciences of The Czech Republic

LigandPNGBDBM234295(Met-PH (2))
Affinity DataKi:  2.20E+4nM ΔG°:  -26.6kJ/molepH: 8.4 T: 2°CAssay Description:LAP was assayed in 75 mM triethanolamine hydrochloride buffer (pH = 8.4, containing 5 mM MgCl2) at 25°C. The substrate (L-leucine-p-nitroanilide) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytosol aminopeptidase [33-68,L62W](Pig)
Academy of Sciences of The Czech Republic

LigandPNGBDBM234294(Met-P (1))
Affinity DataKi:  2.26E+4nM ΔG°:  -26.5kJ/molepH: 8.4 T: 2°CAssay Description:LAP was assayed in 75 mM triethanolamine hydrochloride buffer (pH = 8.4, containing 5 mM MgCl2) at 25°C. The substrate (L-leucine-p-nitroanilide) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytosol aminopeptidase [33-68,L62W](Pig)
Academy of Sciences of The Czech Republic

LigandPNGBDBM50316030(1-aminopentylphosphonic acid | CHEMBL1089899 | Nle...)
Affinity DataKi:  5.80E+4nM ΔG°:  -24.2kJ/molepH: 8.4 T: 2°CAssay Description:LAP was assayed in 75 mM triethanolamine hydrochloride buffer (pH = 8.4, containing 5 mM MgCl2) at 25°C. The substrate (L-leucine-p-nitroanilide) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytosol aminopeptidase [33-68,L62W](Pig)
Academy of Sciences of The Czech Republic

LigandPNGBDBM234296(Nle-PH (4))
Affinity DataKi:  7.39E+4nM ΔG°:  -23.6kJ/molepH: 8.4 T: 2°CAssay Description:LAP was assayed in 75 mM triethanolamine hydrochloride buffer (pH = 8.4, containing 5 mM MgCl2) at 25°C. The substrate (L-leucine-p-nitroanilide) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytosol aminopeptidase [33-68,L62W](Pig)
Academy of Sciences of The Czech Republic

LigandPNGBDBM234299(Nle-ψ[P(O)(OH)O]-L-AlaOMe (7))
Affinity DataKi:  2.19E+5nM ΔG°:  -20.9kJ/molepH: 8.4 T: 2°CAssay Description:LAP was assayed in 75 mM triethanolamine hydrochloride buffer (pH = 8.4, containing 5 mM MgCl2) at 25°C. The substrate (L-leucine-p-nitroanilide) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetCytosol aminopeptidase [33-68,L62W](Pig)
Academy of Sciences of The Czech Republic

LigandPNGBDBM234298(Nle-ψ[P(O)(OH)O]-L-Ala (6))
Affinity DataKi:  2.69E+5nM ΔG°:  -20.4kJ/molepH: 8.4 T: 2°CAssay Description:LAP was assayed in 75 mM triethanolamine hydrochloride buffer (pH = 8.4, containing 5 mM MgCl2) at 25°C. The substrate (L-leucine-p-nitroanilide) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed