Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50039219
LigandPNGBDBM50321851(CHEMBL1173240 | US8796328, D | (R)-8-{5-[3-Methyl-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321857(8-{4-(4-Fluorophenyl)-5-[4-(trifluoromethyl)phenyl...)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321856(4-{2-[7-Hydroxy-5,6,7,8-tetrahydronaphthalen-1-yla...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321853(8-{4-Ethyl-5-[4-(trifluoromethyl)phenyl]oxazol-2-y...)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321850(8-{5-[3-Methyl-4-(trifluoromethyl)phenyl]oxazol-2-...)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321852((S)-8-{5-[3-Methyl-4-(trifluoromethyl)phenyl]oxazo...)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321836(8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-...)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321855(8-{4-Bromo-5-[4-(trifluoromethyl)phenyl]oxazol-2-y...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321839(8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}n...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321845(8-[5-(4-Chlorophenyl)oxazol-2-ylamino]-1,2,3,4-tet...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321851(CHEMBL1173240 | US8796328, D | (R)-8-{5-[3-Methyl-...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321844(8-[5-(4-tert-Butylphenyl)oxazol-2-ylamino]-1,2,3,4...)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321843(8-(5-p-tolyloxazol-2-ylamino)-1,2,3,4-tetrahydrona...)
Affinity DataIC50: 62nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321846(8-[5-(4-Methoxyphenyl)oxazol-2-ylamino]-1,2,3,4-te...)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321847(8-{5-[4-(Pyrrolidin-1-yl)phenyl]oxazol-2-ylamino}-...)
Affinity DataIC50: 101nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321838(N-(1H-indazol-4-yl)-5-[4-(trifluoromethyl)phenyl]o...)
Affinity DataIC50: 101nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321854(8-{4-Isopropyl-5-[4-(trifluoromethyl)phenyl]oxazol...)
Affinity DataIC50: 114nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321834(5-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-...)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321831(N-(7-methoxy-5,6,7,8-tetrahydronaphthalen-1-yl)-5-...)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321842(8-(5-m-Tolyloxazol-2-ylamino)-1,2,3,4-tetrahydrona...)
Affinity DataIC50: 157nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321840(8-(5-Phenyloxazol-2-ylamino)-1,2,3,4-tetrahydronap...)
Affinity DataIC50: 187nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321837(N-(isoquinolin-5-yl)-5-[4-(trifluoromethyl)phenyl]...)
Affinity DataIC50: 229nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321832(8-[Methyl{5-[4-(trifluoromethyl)phenyl]oxazol-2-yl...)
Affinity DataIC50: 277nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321830(N1-{5-[4-(trifluoromethyl)phenyl]oxazol-2-yl}-5,6,...)
Affinity DataIC50: 327nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321835(8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-...)
Affinity DataIC50: 374nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321841(8-(5-o-Tolyloxazol-2-ylamino)-1,2,3,4-tetrahydrona...)
Affinity DataIC50: 416nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321833(2-Methyl-8-{5-[4-(trifluoromethyl)phenyl]oxazol-2-...)
Affinity DataIC50: 840nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321849(8-(4-Phenyloxazol-2-ylamino)-1,2,3,4-tetrahydronap...)
Affinity DataIC50: 864nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321848(8-(5-Benzyloxazol-2-ylamino)-1,2,3,4-tetrahydronap...)
Affinity DataIC50: 1.82E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 receptor expressed in human 1321 cells assessed as inhibition of capsaicin-induced in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321851(CHEMBL1173240 | US8796328, D | (R)-8-{5-[3-Methyl-...)
Affinity DataIC50: 3.70E+4nMAssay Description:Antagonist activity at rat TRPV2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321851(CHEMBL1173240 | US8796328, D | (R)-8-{5-[3-Methyl-...)
Affinity DataIC50: 4.40E+4nMAssay Description:Antagonist activity at human TRPM8 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321851(CHEMBL1173240 | US8796328, D | (R)-8-{5-[3-Methyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human TRPV1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321851(CHEMBL1173240 | US8796328, D | (R)-8-{5-[3-Methyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human TRPV4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
LigandPNGBDBM50321851(CHEMBL1173240 | US8796328, D | (R)-8-{5-[3-Methyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human TRPV3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed