Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50031990
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322851(sodium 3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimi...)
Affinity DataIC50: 2nMAssay Description:Binding affinity to FLAP in human PMN by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322851(sodium 3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimi...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322851(sodium 3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimi...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322851(sodium 3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322851(sodium 3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322851(sodium 3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed