Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50039285
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326559(4-(9,10-dioxo-4-(phenylamino)-5,8,9,10-tetrahydroa...)
Affinity DataIC50: 3.60E+3nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326557(NSC45576, 2 | CHEMBL1253920 | (E)-5-((2-hydroxynap...)
Affinity DataIC50: 3.90E+3nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase B assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326562(8-phenyl-1-thia-4,8-diazaspiro[4.5]decane-3-carbox...)
Affinity DataIC50: 4.00E+3nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326559(4-(9,10-dioxo-4-(phenylamino)-5,8,9,10-tetrahydroa...)
Affinity DataIC50: 4.50E+3nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase B assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326563(2-amino-3-(3,5-dibromo-4-hydroxyphenyl)propanoic a...)
Affinity DataIC50: 4.60E+3nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326561(2-(2,3-dihydro-1H-pyrrolo[3,4-b]quinolin-3-yl)acet...)
Affinity DataIC50: 5.50E+3nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326559(4-(9,10-dioxo-4-(phenylamino)-5,8,9,10-tetrahydroa...)
Affinity DataIC50: 5.50E+3nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326557(NSC45576, 2 | CHEMBL1253920 | (E)-5-((2-hydroxynap...)
Affinity DataIC50: 5.50E+3nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326561(2-(2,3-dihydro-1H-pyrrolo[3,4-b]quinolin-3-yl)acet...)
Affinity DataIC50: 8.10E+3nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326557(NSC45576, 2 | CHEMBL1253920 | (E)-5-((2-hydroxynap...)
Affinity DataIC50: 8.10E+3nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326560(2-amino-3-(5-oxo-5H-benzo[a]phenoxazin-10-yl)propa...)
Affinity DataIC50: 1.30E+4nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326560(2-amino-3-(5-oxo-5H-benzo[a]phenoxazin-10-yl)propa...)
Affinity DataIC50: 3.10E+4nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase B assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326558(10,13-dimethyl-17-(2-(6-thioxo-3H-purin-9(6H)-yl)a...)
Affinity DataIC50: 3.50E+4nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326564(2-amino-3-(6-nitro-1H-indol-3-yl)propanoic acid | ...)
Affinity DataIC50: 5.10E+4nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326565(2-(hydroxyimino)-3-(quinolin-4-yl)propanoic acid |...)
Affinity DataIC50: 7.20E+4nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326566(2-hydroxy-3-(pyridin-2-yl)propanoic acid | CHEMBL1...)
Affinity DataIC50: 8.80E+4nMpH: 7.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326558(10,13-dimethyl-17-(2-(6-thioxo-3H-purin-9(6H)-yl)a...)
Affinity DataIC50: 9.30E+4nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326560(2-amino-3-(5-oxo-5H-benzo[a]phenoxazin-10-yl)propa...)
Affinity DataIC50: 1.08E+5nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50326558(10,13-dimethyl-17-(2-(6-thioxo-3H-purin-9(6H)-yl)a...)
Affinity DataIC50: 1.35E+5nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase B assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50024592((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...)
Affinity DataIC50: 1.39E+5nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase B assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50024592((S)-1-Ammonium-2-phenyl-ethanephosphonic acid anio...)
Affinity DataIC50: 2.23E+5nMpH: 5.0Assay Description:Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed