Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 4817
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  3.70E+3nM ΔG°:  -31.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  3.60E+4nM ΔG°:  -25.4kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataKi:  9.90E+4nM ΔG°:  -22.9kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataKi:  1.05E+5nM ΔG°:  -22.7kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM4078(Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-...)
Affinity DataKi:  1.46E+5nM ΔG°:  -21.9kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM4078(Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-...)
Affinity DataKi:  2.07E+5nM ΔG°:  -21.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM50214744(Ferulic acid (M5) | ferulic acid | CHEMBL32749 | (...)
Affinity DataKi:  2.10E+5nM ΔG°:  -21.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM50214744(Ferulic acid (M5) | ferulic acid | CHEMBL32749 | (...)
Affinity DataKi:  4.08E+5nM ΔG°:  -19.3kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM4374(p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...)
Affinity DataKi:  4.41E+5nM ΔG°:  -19.2kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM4374(p-Coumaric Acid | p-hydroxycinnamic acid (M4) | CH...)
Affinity DataKi:  5.37E+5nM ΔG°:  -18.7kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM26194(4-Hydroxybenzoate, III | CHEMBL441343 | p-Hydroxyb...)
Affinity DataKi:  6.75E+5nM ΔG°:  -18.1kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM50187132(Syringic acid | 3,5-Dimethoxy-4-hydroxybenzoic aci...)
Affinity DataKi:  6.95E+5nM ΔG°:  -18.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM50085536(Gallic Acid, F | 3,4,5-Trihydroxybenzoate, X | CHE...)
Affinity DataKi:  7.58E+5nM ΔG°:  -17.8kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM50187132(Syringic acid | 3,5-Dimethoxy-4-hydroxybenzoic aci...)
Affinity DataKi:  9.19E+5nM ΔG°:  -17.3kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM26194(4-Hydroxybenzoate, III | CHEMBL441343 | p-Hydroxyb...)
Affinity DataKi:  1.06E+6nM ΔG°:  -17.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM50085536(Gallic Acid, F | 3,4,5-Trihydroxybenzoate, X | CHE...)
Affinity DataKi:  1.05E+6nM ΔG°:  -17.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2011
Entry Details Article
PubMed