Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50039187
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  10.2nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50143282((1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  300nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50321015(4-Methyl-3-oxa-4,10-diazatricyclo[6.3.1.0'2,6]dode...)
Affinity DataKi:  9.50E+3nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50321023((-)-Norferruginine | CHEMBL1164304)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50321018(and 5-bromo-3-oxa-4,11-diazatricyclo[6.2.1.0'2,6]u...)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50321020(5-Methoxy-3-oxa-4,11-diazatricyclo[6.2.1.0'2,6]und...)
Affinity DataKi:  2.82E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50321013(3-bromo-5-oxa-4,10-diazatricyclo[6.3.1.0'2,6]dodec...)
Affinity DataKi:  2.85E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50321019(3-Methoxy-5-oxa-4,11-diazatricyclo[6.2.1.0'2,6]und...)
Affinity DataKi:  6.80E+4nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50321016(4-Methyl-5-oxa-4,10-diazatricyclo[6.3.1.0'2,6]dode...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50321021(4-Methyl-5-oxa-4,11-diazatricyclo[6.2.1.0'2,6]unde...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50321022(4-Methyl-3-oxa-4,11-diazatricyclo[6.2.1.0'2,6]unde...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50321017(3-Bromo-5-oxa-4,11-diazatricyclo[6.2.1.0'2,6]undec...)
Affinity DataKi:  1.09E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50378786(CHEMBL1794974)
Affinity DataKi:  1.70E+5nMAssay Description:Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed