Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50031813
LigandPNGBDBM50319739(3,3-dimethyl-N-(4-(2-(4-sulfamoylphenylamino)pyrim...)
Affinity DataIC50: 10nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50303035(4-(4-(5-methylthiophen-2-yl)pyrimidin-2-ylamino)be...)
Affinity DataIC50: 19nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319743(N-(4-(2-(4-sulfamoylphenylamino)pyrimidin-4-yl)phe...)
Affinity DataIC50: 20nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319737(4-(4-(4-methoxyphenyl)pyrimidin-2-ylamino)benzenes...)
Affinity DataIC50: 40nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319741(2-phenyl-N-(4-(2-(4-sulfamoylphenylamino)pyrimidin...)
Affinity DataIC50: 50nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319759(N-(2-hydroxyethyl)-4-(4-(thiophen-3-yl)pyrimidin-2...)
Affinity DataIC50: 130nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319757(N-(3-(dimethylamino)propyl)-4-(4-(thiophen-3-yl)py...)
Affinity DataIC50: 170nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319753(4-(4-(thiophen-3-yl)pyrimidin-2-ylamino)benzenesul...)
Affinity DataIC50: 180nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319755(N-(2-(dimethylamino)ethyl)-4-(4-(thiophen-3-yl)pyr...)
Affinity DataIC50: 230nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319751(methyl 3-oxo-3-(2-(4-sulfamoylphenylamino)-5,6-dih...)
Affinity DataIC50: 280nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319745(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 310nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319738(4-(8-methoxy-5,6-dihydrobenzo[h]quinazolin-2-ylami...)
Affinity DataIC50: 420nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319744(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 510nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319756(4-(5,6-dihydrothieno[2,3-h]quinazolin-2-ylamino)-N...)
Affinity DataIC50: 510nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319738(4-(8-methoxy-5,6-dihydrobenzo[h]quinazolin-2-ylami...)
Affinity DataIC50: 550nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319758(4-(5,6-dihydrothieno[2,3-h]quinazolin-2-ylamino)-N...)
Affinity DataIC50: 620nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319737(4-(4-(4-methoxyphenyl)pyrimidin-2-ylamino)benzenes...)
Affinity DataIC50: 640nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319756(4-(5,6-dihydrothieno[2,3-h]quinazolin-2-ylamino)-N...)
Affinity DataIC50: 770nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319755(N-(2-(dimethylamino)ethyl)-4-(4-(thiophen-3-yl)pyr...)
Affinity DataIC50: 770nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319758(4-(5,6-dihydrothieno[2,3-h]quinazolin-2-ylamino)-N...)
Affinity DataIC50: 780nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319754(4-(5,6-dihydrothieno[2,3-h]quinazolin-2-ylamino)be...)
Affinity DataIC50: 790nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319754(4-(5,6-dihydrothieno[2,3-h]quinazolin-2-ylamino)be...)
Affinity DataIC50: 800nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319740(3,3-dimethyl-N-(2-(4-sulfamoylphenylamino)-5,6-dih...)
Affinity DataIC50: 820nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319744(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 830nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319745(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 970nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319757(N-(3-(dimethylamino)propyl)-4-(4-(thiophen-3-yl)py...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319750(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319760(4-(5,6-dihydrothieno[2,3-h]quinazolin-2-ylamino)-N...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319740(3,3-dimethyl-N-(2-(4-sulfamoylphenylamino)-5,6-dih...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319735(4-(5,6-dihydrobenzo[h]quinazolin-2-ylamino)benzene...)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319750(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319749(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319748(3-methyl-N-(2-(4-sulfamoylphenylamino)-5,6-dihydro...)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319746(2-(4-methoxyphenyl)-N-(2-(4-sulfamoylphenylamino)-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319753(4-(4-(thiophen-3-yl)pyrimidin-2-ylamino)benzenesul...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50303035(4-(4-(5-methylthiophen-2-yl)pyrimidin-2-ylamino)be...)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319742(2-phenyl-N-(2-(4-sulfamoylphenylamino)-5,6-dihydro...)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319735(4-(5,6-dihydrobenzo[h]quinazolin-2-ylamino)benzene...)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319746(2-(4-methoxyphenyl)-N-(2-(4-sulfamoylphenylamino)-...)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319747(3-methyl-N-(2-(4-sulfamoylphenylamino)-5,6-dihydro...)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319760(4-(5,6-dihydrothieno[2,3-h]quinazolin-2-ylamino)-N...)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319749(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319752(N-(2-(4-sulfamoylphenylamino)-5,6-dihydrobenzo[h]q...)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319742(2-phenyl-N-(2-(4-sulfamoylphenylamino)-5,6-dihydro...)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of FLAG-tagged IKK-beta after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319739(3,3-dimethyl-N-(4-(2-(4-sulfamoylphenylamino)pyrim...)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319759(N-(2-hydroxyethyl)-4-(4-(thiophen-3-yl)pyrimidin-2...)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319736(4-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrim...)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319741(2-phenyl-N-(4-(2-(4-sulfamoylphenylamino)pyrimidin...)
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319747(3-methyl-N-(2-(4-sulfamoylphenylamino)-5,6-dihydro...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandPNGBDBM50319743(N-(4-(2-(4-sulfamoylphenylamino)pyrimidin-4-yl)phe...)
Affinity DataIC50: 6.91E+3nMAssay Description:Inhibition of IKK-beta expressed in human HeLa cells transfected with pNFkappaB-luciferase assessed inhibition of TNF-alpha-induced NF-kappaB express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 53 total ) | Next | Last >>
Jump to: