Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50031870
TargetAlpha-galactosidase(Arabian coffee)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50: 3nMpH: 6.5Assay Description:Inhibition of coffee bean alpha-galactosidase assessed as p-nitrophenol release at pH 6.5 by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-galactosidase A(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataIC50: 690nMAssay Description:Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-galactosidase(Arabian coffee)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataIC50: 780nMpH: 6.5Assay Description:Inhibition of coffee bean alpha-galactosidase assessed as p-nitrophenol release at pH 6.5 by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-galactosidase(Arabian coffee)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320826(beta-1-C-Butyl-1-deoxygalactonojirimycin | CHEMBL1...)
Affinity DataIC50: 1.20E+3nMpH: 6.5Assay Description:Inhibition of coffee bean alpha-galactosidase assessed as p-nitrophenol release at pH 6.5 by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-galactosidase(Arabian coffee)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320827(beta-1-C-butenyl-1-deoxygalactonojirimycin | CHEMB...)
Affinity DataIC50: 2.00E+3nMpH: 6.5Assay Description:Inhibition of coffee bean alpha-galactosidase assessed as p-nitrophenol release at pH 6.5 by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetLactase/phlorizin hydrolase(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of rat intestinal lactase assessed as p-nitrophenol release by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProbable alpha-glucosidase Os06g0675700(Rice)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320826(beta-1-C-Butyl-1-deoxygalactonojirimycin | CHEMBL1...)
Affinity DataIC50: 1.00E+4nMpH: 5.0Assay Description:Inhibition of rice alpha-glucosidase assessed as D-glucose release at pH 5 after 10 to 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320826(beta-1-C-Butyl-1-deoxygalactonojirimycin | CHEMBL1...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetBeta-glucosidase A(Caldocellum saccharolyticum)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataIC50: 1.90E+4nMpH: 5.0Assay Description:Inhibition of Caldocellum saccharolyticum beta-glucosidase assessed as p-nitrophenol release at pH 5 by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320827(beta-1-C-butenyl-1-deoxygalactonojirimycin | CHEMB...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProbable alpha-glucosidase Os06g0675700(Rice)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320827(beta-1-C-butenyl-1-deoxygalactonojirimycin | CHEMB...)
Affinity DataIC50: 4.50E+4nMpH: 5.0Assay Description:Inhibition of rice alpha-glucosidase assessed as D-glucose release at pH 5 after 10 to 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetLactase/phlorizin hydrolase(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of rat intestinal lactase assessed as p-nitrophenol release by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetBeta-glucosidase A(Caldocellum saccharolyticum)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320826(beta-1-C-Butyl-1-deoxygalactonojirimycin | CHEMBL1...)
Affinity DataIC50: 1.52E+5nMpH: 5.0Assay Description:Inhibition of Caldocellum saccharolyticum beta-glucosidase assessed as p-nitrophenol release at pH 5 by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProbable alpha-glucosidase Os06g0675700(Rice)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataIC50: 1.71E+5nMpH: 5.0Assay Description:Inhibition of rice alpha-glucosidase assessed as D-glucose release at pH 5 after 10 to 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320825(6-O-beta-D-glucopyranosyl-2,3-dideoxy-beta-1-C-eth...)
Affinity DataIC50: 2.24E+5nMAssay Description:Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-galactosidase(Arabian coffee)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320825(6-O-beta-D-glucopyranosyl-2,3-dideoxy-beta-1-C-eth...)
Affinity DataIC50: 3.18E+5nMpH: 6.5Assay Description:Inhibition of coffee bean alpha-galactosidase assessed as p-nitrophenol release at pH 6.5 by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetBeta-glucosidase A(Caldocellum saccharolyticum)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50: 3.67E+5nMpH: 5.0Assay Description:Inhibition of Caldocellum saccharolyticum beta-glucosidase assessed as p-nitrophenol release at pH 5 by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetTissue alpha-L-fucosidase(Bovine)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataIC50: 5.03E+5nMpH: 5.5Assay Description:Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release at pH 5.5 by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProbable alpha-glucosidase Os06g0675700(Rice)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320825(6-O-beta-D-glucopyranosyl-2,3-dideoxy-beta-1-C-eth...)
Affinity DataIC50: 6.70E+5nMpH: 5.0Assay Description:Inhibition of rice alpha-glucosidase assessed as D-glucose release at pH 5 after 10 to 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetBeta-glucosidase A(Caldocellum saccharolyticum)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50320827(beta-1-C-butenyl-1-deoxygalactonojirimycin | CHEMB...)
Affinity DataIC50: 1.00E+6nMpH: 5.0Assay Description:Inhibition of Caldocellum saccharolyticum beta-glucosidase assessed as p-nitrophenol release at pH 5 by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAlpha-galactosidase A(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataKi:  500nMAssay Description:Competitive inhibition of human lysosome alpha-galactosidase by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)