Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50039137
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50381677(U-69593 | CHEMBL1256748)
Affinity DataEC50:  80nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316611((+)-1-{(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316619((+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataEC50:  820nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316615((+)-Methyl(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acet...)
Affinity DataEC50:  87nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316622((S)-methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-((S)...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataKi:  0.340nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50027433(GR-89696 | CHEMBL603370)
Affinity DataKi:  0.360nMAssay Description:Displacement of [(3)H]U69593 from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50381677(U-69593 | CHEMBL1256748)
Affinity DataKi:  0.970nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316615((+)-Methyl(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acet...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  1.5nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316621((R)-methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-((R)...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316615((+)-Methyl(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acet...)
Affinity DataKi:  6nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316619((+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316611((+)-1-{(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  15nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316619((+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  70nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316613((1S,2S,5R)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)...)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316611((+)-1-{(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]Cl977 from human kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316615((+)-Methyl(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acet...)
Affinity DataKi:  140nMAssay Description:Displacement of [(3)H]U69593 from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316616((-)-Methyl(1R,2S,5S)-8-[2-(3,4-Dichlorophenyl)acet...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316618((-)-1-[(1R,2R,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  152nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316617((+)-1-[(1S,2S,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  180nMAssay Description:Displacement of [(3)H]U69593 from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316618((-)-1-[(1R,2R,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  198nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316617((+)-1-[(1S,2S,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  421nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316620((-)-1-[(1R,2S,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  433nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316612((-)-1-{(1R,2S,5S)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi:  464nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316619((+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  470nMAssay Description:Displacement of [(3)H]U69593 from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316614((1R,2R,5S)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)...)
Affinity DataKi:  515nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316611((+)-1-{(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi:  650nMAssay Description:Displacement of [(3)H]U69593 from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316613((1S,2S,5R)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)...)
Affinity DataKi:  850nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316618((-)-1-[(1R,2R,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  920nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316609((+)-1-{(1S,2S,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]deltorphine-2 from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316610((-)-1-{(1R,2R,5S)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]deltorphine-2 from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316611((+)-1-{(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]deltorphine-2 from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316619((+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316613((1S,2S,5R)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]deltorphine-2 from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316616((-)-Methyl(1R,2S,5S)-8-[2-(3,4-Dichlorophenyl)acet...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]deltorphine-2 from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316612((-)-1-{(1R,2S,5S)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]deltorphine-2 from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316620((-)-1-[(1R,2S,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]deltorphine-2 from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316609((+)-1-{(1S,2S,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316619((+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]deltorphine-2 from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316610((-)-1-{(1R,2R,5S)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316620((-)-1-[(1R,2S,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316618((-)-1-[(1R,2R,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]deltorphine-2 from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316620((-)-1-[(1R,2S,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi: >1.00E+3nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
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