Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50031778
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318942(4-(2,4-diethyl-1-(2-methoxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318939(2-(3-(4-cyanophenoxy)-2,4-diethyl-1H-pyrrol-1-yl)-...)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318937(4-(2,4-diethyl-1-(methylsulfonylmethyl)-1H-pyrrol-...)
Affinity DataIC50: 56nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318933(4-(2,4-dicyclopropyl-1-(methylsulfonylmethyl)-1H-p...)
Affinity DataIC50: 71nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 131nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318940(2-(3-(4-cyanophenoxy)-2,4-diethyl-1H-pyrrol-1-yl)a...)
Affinity DataIC50: 173nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318935(4-(2,4-diethyl-1-(3-hydroxypropyl)-1H-pyrrol-3-ylo...)
Affinity DataIC50: 204nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318944(4-(2,4-diethyl-1H-pyrrol-3-yloxy)benzonitrile | CH...)
Affinity DataIC50: 224nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318938(2-(3-(4-cyanophenoxy)-2,4-diethyl-1H-pyrrol-1-yl)-...)
Affinity DataIC50: 886nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318936(4-(1-(2-aminoethyl)-2,4-diethyl-1H-pyrrol-3-yloxy)...)
Affinity DataIC50: 1.13E+3nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of estrogen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318943(4-(2,4-diethyl-1-(2-hydroxyethyl)-1H-pyrrol-3-ylox...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318941(2-(3-(4-cyanophenoxy)-2,4-diethyl-1H-pyrrol-1-yl)a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of estrogen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318934(2-(3-(4-cyanophenoxy)-2,4-dicyclopropyl-1H-pyrrol-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells by alkaline phosphatase releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed