Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50031753
TargetMu-type opioid receptor(Mouse)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataEC50:  85.5nMAssay Description:Agonist activity at mu opioid receptor in Swiss albino mouse ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318415(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-(cyclopropylme...)
Affinity DataEC50:  90nMAssay Description:Agonist activity at mu opioid receptor in Swiss albino mouse ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318412(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-propoxy-6-deme...)
Affinity DataEC50:  1.99nMAssay Description:Agonist activity at mu opioid receptor in Swiss albino mouse ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318413(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-ethoxy-6-demet...)
Affinity DataEC50:  44nMAssay Description:Agonist activity at mu opioid receptor in Swiss albino mouse ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318414(7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahy...)
Affinity DataEC50:  11.9nMAssay Description:Agonist activity at mu opioid receptor in Swiss albino mouse ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318416(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-phenyl-6-demet...)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318412(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-propoxy-6-deme...)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318415(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-(cyclopropylme...)
Affinity DataIC50: 0.140nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318413(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-ethoxy-6-demet...)
Affinity DataIC50: 0.180nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318414(7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahy...)
Affinity DataIC50: 0.540nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataIC50: 5.64nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318413(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-ethoxy-6-demet...)
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]deltorphin-2 from delta opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318412(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-propoxy-6-deme...)
Affinity DataIC50: 320nMAssay Description:Displacement of [3H]deltorphin-2 from delta opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataIC50: 404nMAssay Description:Displacement of [3H]deltorphin-2 from delta opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318416(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-phenyl-6-demet...)
Affinity DataIC50: 440nMAssay Description:Displacement of [3H]deltorphin-2 from delta opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318415(7alpha-(1-Hydroxy-1-methyl-ethyl)-6-(cyclopropylme...)
Affinity DataIC50: 650nMAssay Description:Displacement of [3H]deltorphin-2 from delta opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318414(7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahy...)
Affinity DataIC50: 1.35E+3nMAssay Description:Displacement of [3H]deltorphin-2 from delta opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed