Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50031742
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318241((4,6-dimethylpyrimidin-2-ylamino)(2-(5-fluoro-1H-i...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318244((R)-N-(3-phenyl-1H-1,2,4-triazol-5-yl)-2-(m-tolylo...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM57851(1-(4,6-dimethyl-2-pyrimidinyl)-2-[2-(1H-indol-3-yl...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318243((4,6-dimethylpyrimidin-2-ylamino)(2-(thiophen-3-yl...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318251((4,6-dimethylpyrimidin-2-ylamino)(2-(6-methoxy-1H-...)
Affinity DataKi:  600nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50153337((4,6-dimethylpyrimidin-2-ylamino)(4-methoxypheneth...)
Affinity DataKi:  900nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318245(1,3-dimethyl-8-(m-tolylamino)-1H-purine-2,6(3H,7H)...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318246(N-(4,6-dimethylpyrimidin-2-yl)-6-methyl-1H-benzo[d...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318247(2-amino-7-methoxy-4-(pyridin-4-yl)dibenzo[b,d]fura...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318244((R)-N-(3-phenyl-1H-1,2,4-triazol-5-yl)-2-(m-tolylo...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318250(6-(3,4-dimethoxyphenyl)-2-(phenylamino)pyrimidin-4...)
Affinity DataKi:  3.60E+3nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318248((2-(1H-indol-3-yl)ethylamino)(pyrimidin-2-ylamino)...)
Affinity DataKi:  5.90E+3nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50318249((E)-N-(amino(4-methylquinazolin-2-ylamino)methylen...)
Affinity DataKi:  8.80E+3nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed