Compile Data Set for Download or QSAR
Report error Found 122 Enz. Inhib. hit(s) with all data for entry = 50039146
TargetDNA topoisomerase 1(Rat)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 660nMAssay Description:Inhibition of rat liver DNA topoisomerase 1 preincubated before addition of DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Rat)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat liver DNA topoisomerase 1 treated simultaneously with DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317518(Aesculioside IId | CHEMBL1095016)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317510(AesculiosideIV-23C1 | CHEMBL1094358)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317508(Aesculioside IV-23E | CHEMBL1094674)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317507(Aesculioside IV-23D1 | CHEMBL1094675)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317505(Aesculioside IVa | CHEMBL1094677)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317503(Aesculioside IVc | CHEMBL1094679)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317511(Aesculioside IVb | CHEMBL1094681)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317527(Aesculioside IIIb | CHEMBL1094683)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317521(Aesculioside IIIa | CHEMBL1094690)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317519(Aesculioside IIc | CHEMBL1095014)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317518(Aesculioside IId | CHEMBL1095016)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human DNA topoisomerase 1 at free enzyme stateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317507(Aesculioside IV-23D1 | CHEMBL1094675)
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317508(Aesculioside IV-23E | CHEMBL1094674)
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317511(Aesculioside IVb | CHEMBL1094681)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317514(Aesculioside IIIe | CHEMBL1095027)
Affinity DataIC50: 4.51E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317516(Aesculioside IIId | CHEMBL1095025)
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317503(Aesculioside IVc | CHEMBL1094679)
Affinity DataIC50: 4.97E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317505(Aesculioside IVa | CHEMBL1094677)
Affinity DataIC50: 5.18E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317510(AesculiosideIV-23C1 | CHEMBL1094358)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317515(Aesculioside IIIf | CHEMBL1095026)
Affinity DataIC50: 5.37E+4nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317532(Aesculioside IIa | CHEMBL1094691)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317519(Aesculioside IIc | CHEMBL1095014)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317521(Aesculioside IIIa | CHEMBL1094690)
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317512(Aesculioside IIIc | CHEMBL1095341)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317527(Aesculioside IIIb | CHEMBL1094683)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317534(Damara-20(22), 24-dien-3, 6, 12-trine | CHEMBL1096...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317535(Gynosaponin S | CHEMBL1095009)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317536(20(R)-Ginsenoside Rg3 | CHEMBL1095008)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317537(20(S)-ginsenoside Rg3 | CHEMBL398412)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317538(Ginsenoside F2 | CHEMBL1095007)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317539(Ginsenoside Rd | ginsenoside-Rd | CHEMBL473659)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317540(ginsenoside-Rb3 | ginsenoside Rb3 | CHEMBL507688)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317541(ginsenoside-Rb1 | Ginsenoside Rb1 | CHEMBL501515)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317542(20(R)-Ginsenoside Rg2 | CHEMBL1095006)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317543(20(S)-Ginsenoside Rg2 | CHEMBL1095005)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317544(Ginsenoside F3 | CHEMBL1095004)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50378778(CHEMBL583152)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50378779(CHEMBL510095)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50377927(Clerodol | Fagarasterol | Farganasterol | Monogyno...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317548(lupeol 3-acetate | CHEMBL1097034)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317549(2, 3-dihydroxy-12-ursen-28-oic acid | CHEMBL109703...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50241956(urs-12-en-3beta-ol | alpha-amyrin | (3S,4aR,6aR,6b...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317550(3-O-beta-D-glucopyranosyl quinovic acid 28-O-alpha...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317551(3-O-beta-D-glucopyranosyl-(1-4)-alpha-L-rhamnopyra...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317552(3-O-beta-D-glucopyranosyl quinovic acid28-O-beta-D...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317553(3-O-alpha-L-rhamnopyranosyl quinovic acid | CHEMBL...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317554((1S,2R,4aS,6aR,6bR,8aR,10S,12aR,12bR,14bS)-1,2,6b,...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317555(3-O-beta-6-deoxy-D-glucopyranosyl cincholic acid28...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
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