Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50031596
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315949((S)-N-(4-aminobutyl)-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315959(N-(4-aminobutyl)-N-(2-(4-hydroxycyclohexylamino)py...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315931((S)-N-ethyl-3-methyl-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315917((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315958(N-(4-aminobutyl)-N-(2-(isopropylamino)pyrimidin-4-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315951(N-(2-(isopropylamino)pyrimidin-4-yl)-N-(piperidin-...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315960((S)-N-(4-aminobutyl)-N-(2-(1-methoxypropan-2-ylami...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315938((S)-N-ethyl-2-fluoro-5-methyl-N-(2-(1-phenylethyla...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315937((S)-N-ethyl-4-fluoro-3-methyl-N-(2-(1-phenylethyla...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315922((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315943((S)-N-(2-(1-phenylethylamino)pyrimidin-4-yl)-N-(pi...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315916((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315936((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315934((S)-N,3-diethyl-N-(2-(1-phenylethylamino)pyrimidin...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315920((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315919((S)-N-(3-(methylsulfonyl)propyl)-N-(2-(1-phenyleth...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315933((S)-N-ethyl-2,3-dimethyl-N-(2-(1-phenylethylamino)...)
Affinity DataIC50: 81nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315929((S)-3-chloro-N-ethyl-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50: 81nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315921((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315932((S)-N-ethyl-3,4-dimethyl-N-(2-(1-phenylethylamino)...)
Affinity DataIC50: 91nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315950((S)-N-(4-hydroxybutyl)-N-(2-(1-phenylethylamino)py...)
Affinity DataIC50: 96nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315935((S)-3-cyclopropyl-N-ethyl-N-(2-(1-phenylethylamino...)
Affinity DataIC50: 104nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315925((S)-N-ethyl-1-methyl-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50: 154nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315942((S)-N-(2-(1-phenylethylamino)pyrimidin-4-yl)-N-((t...)
Affinity DataIC50: 158nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315918((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 164nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315940((S)-N-(cyclopropylmethyl)-N-(2-(1-phenylethylamino...)
Affinity DataIC50: 165nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315926((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 179nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315923((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315924((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 188nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315927((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...)
Affinity DataIC50: 193nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315928((S)-2-chloro-N-ethyl-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50: 267nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315961((S)-N-(4-aminobutyl)-N-(2-(1-hydroxypropan-2-ylami...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315930((S)-4-chloro-N-ethyl-N-(2-(1-phenylethylamino)pyri...)
Affinity DataIC50: 313nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315875((S)-N-ethyl-N-(2-(1-phenylethylamino)pyridin-4-yl)...)
Affinity DataIC50: 313nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315954((S)-N-(2-(1-methoxypropan-2-ylamino)pyrimidin-4-yl...)
Affinity DataIC50: 316nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315941((S)-N-(2-methoxyethyl)-N-(2-(1-phenylethylamino)py...)
Affinity DataIC50: 345nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315952(N-(2-(4-hydroxycyclohexylamino)pyrimidin-4-yl)-N-(...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315953(N-(2-(4-aminocyclohexylamino)pyrimidin-4-yl)-N-(pi...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315939((S)-N-isobutyl-N-(2-(1-phenylethylamino)pyrimidin-...)
Affinity DataIC50: 462nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315956(N-(2-(1-methoxybutan-2-ylamino)pyrimidin-4-yl)-N-(...)
Affinity DataIC50: 530nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315957(N-(2-(cyclopropylamino)pyrimidin-4-yl)-N-(piperidi...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315947((S)-N-(2-(1-phenylethylamino)pyrimidin-4-yl)-N-((1...)
Affinity DataIC50: 673nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315946((S)-4-((N-(2-(1-phenylethylamino)pyrimidin-4-yl)-2...)
Affinity DataIC50: 711nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315866(N-(4-fluorobenzyl)-N-(pyridin-4-yl)-2-naphthamide ...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315955(N-(2-(1-hydroxy-2-methylpropan-2-ylamino)pyrimidin...)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315948((S)-N-(3-aminopropyl)-N-(2-(1-phenylethylamino)pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315945(N-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-N-(pi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315944(N-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-N-(pi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed