Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50031584
TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315775(1-(4-(5-chloro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyr...)
Affinity DataIC50: 9nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315769(GSK-1070916 | 4-[3-(4-N,N-Dimethylcarbamylaminophe...)
Affinity DataIC50: 32nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315776(1-(3-(5-chloro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyr...)
Affinity DataIC50: 67nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315773(N,N-dimethyl-1-(3-(4-(1-methyl-1H-pyrazol-4-yl)-1H...)
Affinity DataIC50: 104nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315774(N,N-dimethyl-1-(4-(4-(1-methyl-1H-pyrazol-4-yl)-1H...)
Affinity DataIC50: 169nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315771(4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyri...)
Affinity DataIC50: 6.16E+3nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315770(4-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine | CH...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed