Compile Data Set for Download or QSAR
Report error Found 87 Enz. Inhib. hit(s) with all data for entry = 50031568
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315438(4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-in...)
Affinity DataIC50: 1nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315438(4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-in...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315439(4,6-dihydroxy-2-((5-methoxy-2-phenyl-1H-indol-3-yl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315445(4,6-dihydroxy-2-((5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315445(4,6-dihydroxy-2-((5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315460(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315466(4,6-dihydroxy-2-((5-methoxy-1,2-dimethyl-1H-indol-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315461(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(2-(4-methy...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315456(2-((1-(3-(dimethylamino)propyl)-5-methoxy-2-methyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315453(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50: 6nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315466(4,6-dihydroxy-2-((5-methoxy-1,2-dimethyl-1H-indol-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315460(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50: 7nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315455(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-morpholi...)
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315462(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(2-morpholi...)
Affinity DataIC50: 9nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315463(2-((1-(2-(dimethylamino)ethyl)-5-methoxy-2-methyl-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315438(4,6-dihydroxy-2-((5-methoxy-2-(pyridin-3-yl)-1H-in...)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315439(4,6-dihydroxy-2-((5-methoxy-2-phenyl-1H-indol-3-yl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315461(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(2-(4-methy...)
Affinity DataIC50: 11nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315462(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(2-morpholi...)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315439(4,6-dihydroxy-2-((5-methoxy-2-phenyl-1H-indol-3-yl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315454(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-(4-methy...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315455(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-morpholi...)
Affinity DataIC50: 18nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315463(2-((1-(2-(dimethylamino)ethyl)-5-methoxy-2-methyl-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315443(4,6-dihydroxy-2-((2-(pyridin-2-yl)-1H-indol-3-yl)m...)
Affinity DataIC50: 22nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315445(4,6-dihydroxy-2-((5-methoxy-2-methyl-1H-indol-3-yl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315449(4,6-dihydroxy-2-((5-methoxy-1H-indol-3-yl)methylen...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315464(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50: 36nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315457(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50: 37nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315459(2-((1-(3-(dimethylamino)propyl)-5-methoxy-1H-indol...)
Affinity DataIC50: 40nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315458(4,6-dihydroxy-2-((5-methoxy-1-(3-morpholinopropyl)...)
Affinity DataIC50: 42nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315466(4,6-dihydroxy-2-((5-methoxy-1,2-dimethyl-1H-indol-...)
Affinity DataIC50: 54nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315437(4,6-dihydroxy-2-((5-methoxy-1-methyl-1H-indol-3-yl...)
Affinity DataIC50: 62nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315455(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-morpholi...)
Affinity DataIC50: 76nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315465(4,6-dihydroxy-2-((1-methyl-2-phenyl-1H-indol-3-yl)...)
Affinity DataIC50: 96nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315437(4,6-dihydroxy-2-((5-methoxy-1-methyl-1H-indol-3-yl...)
Affinity DataIC50: 106nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315453(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50: 108nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315453(4,6-dihydroxy-2-((1-(3-(4-(2-hydroxyethyl)piperazi...)
Affinity DataIC50: 109nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315456(2-((1-(3-(dimethylamino)propyl)-5-methoxy-2-methyl...)
Affinity DataIC50: 118nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315442(2-((2-(4-fluorophenyl)-1H-indol-3-yl)methylene)-4,...)
Affinity DataIC50: 123nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315444(4,6-dihydroxy-2-((2-phenyl-1H-indol-3-yl)methylene...)
Affinity DataIC50: 130nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315454(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(3-(4-methy...)
Affinity DataIC50: 153nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315462(4,6-dihydroxy-2-((5-methoxy-2-methyl-1-(2-morpholi...)
Affinity DataIC50: 155nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315446(2-((5-bromo-2-methyl-1H-indol-3-yl)methylene)-4,6-...)
Affinity DataIC50: 179nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315441(2-((2-(4-chlorophenyl)-1H-indol-3-yl)methylene)-4,...)
Affinity DataIC50: 190nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315446(2-((5-bromo-2-methyl-1H-indol-3-yl)methylene)-4,6-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315464(4,6-dihydroxy-2-((1-(2-(4-(3-hydroxypropyl)piperaz...)
Affinity DataIC50: 215nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315449(4,6-dihydroxy-2-((5-methoxy-1H-indol-3-yl)methylen...)
Affinity DataIC50: 265nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315449(4,6-dihydroxy-2-((5-methoxy-1H-indol-3-yl)methylen...)
Affinity DataIC50: 269nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315440(4,6-dihydroxy-2-((2-(naphthalen-2-yl)-1H-indol-3-y...)
Affinity DataIC50: 280nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50315463(2-((1-(2-(dimethylamino)ethyl)-5-methoxy-2-methyl-...)
Affinity DataIC50: 283nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
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