Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50031567
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315427((1S)-1,5-Anhydro-1-[4-chloro-3-[4-(methylsulfanyl)...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315431((1S)-1,5-Anhydro-1-[4-chloro-3-(4-methylbenzyl)phe...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315423((1S)-1,5-Anhydro-1-[4-chloro-5-(4-ethylbenzyl)-2-m...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315425((1S)-1,5-Anhydro-1-[5-(4-ethylbenzyl)-2-methoxy-4-...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315432((1S)-1,5-Anhydro-1-[4-chloro-3-(4-methoxybenzyl)ph...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315430((1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethylbenzyl)phen...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315436((1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phe...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315426((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315418((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methylphe...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315424((1S)-1,5-Anhydro-1-[2-methoxy-4-methyl-5-[4-(propa...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315429((1S)-1,5-Anhydro-1-[4-chloro-3-[4-(propan-2-yl)ben...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315419((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-fluorophe...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315433((1S)-1,5-Anhydro-1-[2,4-dimethoxy-5-(4-ethoxybenzy...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315420((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methoxyph...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315435((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-hydroxyph...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315428((1S)-1,5-Anhydro-1-[3-(4-tert-butylbenzyl)-4-chlor...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315434((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxyph...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315422((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)phenyl]-1-th...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315431((1S)-1,5-Anhydro-1-[4-chloro-3-(4-methylbenzyl)phe...)
Affinity DataIC50: 209nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 246nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315432((1S)-1,5-Anhydro-1-[4-chloro-3-(4-methoxybenzyl)ph...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315421((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-hydroxyph...)
Affinity DataIC50: 283nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315427((1S)-1,5-Anhydro-1-[4-chloro-3-[4-(methylsulfanyl)...)
Affinity DataIC50: 391nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315420((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methoxyph...)
Affinity DataIC50: 565nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315430((1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethylbenzyl)phen...)
Affinity DataIC50: 602nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315418((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methylphe...)
Affinity DataIC50: 671nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315436((1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phe...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315425((1S)-1,5-Anhydro-1-[5-(4-ethylbenzyl)-2-methoxy-4-...)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315423((1S)-1,5-Anhydro-1-[4-chloro-5-(4-ethylbenzyl)-2-m...)
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315426((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...)
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315435((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-hydroxyph...)
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315433((1S)-1,5-Anhydro-1-[2,4-dimethoxy-5-(4-ethoxybenzy...)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315419((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-fluorophe...)
Affinity DataIC50: 7.96E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315429((1S)-1,5-Anhydro-1-[4-chloro-3-[4-(propan-2-yl)ben...)
Affinity DataIC50: 8.16E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315421((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-hydroxyph...)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315424((1S)-1,5-Anhydro-1-[2-methoxy-4-methyl-5-[4-(propa...)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315422((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)phenyl]-1-th...)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315428((1S)-1,5-Anhydro-1-[3-(4-tert-butylbenzyl)-4-chlor...)
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50315434((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxyph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of glucose uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed