Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50031527
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  351nMAssay Description:Agonist activity at human MC3R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at rat MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314767(trans-N-(2-((S)-1'-((3R,4S)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  620nMAssay Description:Agonist activity at human MC1R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314765(trans-N-(2-((S)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  228nMAssay Description:Agonist activity at human MC1R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at mouse MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314767(trans-N-(2-((S)-1'-((3R,4S)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314766(trans-N-(2-((R)-1'-((3R,4S)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  94nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  1.02E+3nMAssay Description:Agonist activity at human MC1R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314765(trans-N-(2-((S)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataEC50:  997nMAssay Description:Agonist activity at rat MC3R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314765(trans-N-(2-((S)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataIC50: 4.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314767(trans-N-(2-((S)-1'-((3R,4S)-1-tert-butyl-4-(2,4-di...)
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataIC50: 84nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314766(trans-N-(2-((R)-1'-((3R,4S)-1-tert-butyl-4-(2,4-di...)
Affinity DataIC50: 89nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataIC50: 890nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314764(trans-N-(2-((R)-1'-((3S,4R)-1-tert-butyl-4-(2,4-di...)
Affinity DataIC50: 1.94E+3nMAssay Description:Agonist activity at human MC1R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed