Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50032235
LigandPNGBDBM50326075((E)-4-(3-(4-Fluoro-3-nitrophenyl)-2-(4-(trifluorom...)
Affinity DataIC50: 200nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326092((E)-3-(4-Fluoro-3-nitrophenyl)-2-(4-fluorobenzylth...)
Affinity DataIC50: 500nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326090((E)-2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitropheny...)
Affinity DataIC50: 500nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326061((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 500nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326091((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 500nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326076((E)-methyl 4-(2-(4-bromobenzylthio)-3-(4-fluoro-3-...)
Affinity DataIC50: 750nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326061((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 750nMAssay Description:Inhibition of Bcr-Abl after 20 mins by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 750nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326089((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326077((E)-4-(2-(Benzylthio)-3-(4-fluoro-3-nitrophenyl)ac...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326073((E)-4-(3-(4-Bromo-3-nitrophenyl)-2-(2,4-dichlorobe...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326066((E)-4-(2-(4-Fluorobenzylthio)-3-(4-fluoro-3-nitrop...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326074((E)-4-(3-(4-Fluoro-3-nitrophenyl)-2-(4-methylbenzy...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326071((E)-4-(3-(4-Chloro-3-nitrophenyl)-2-(2,4-dichlorob...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326072((E)-4-(3-(4-Fluoro-3-nitrophenyl)-2-(2,4-dichlorob...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326064((E)-4-(2-(4-Chlorobenzylthio)-3-(4-bromo-3-nitroph...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326062((E)-4-(2-(4-Chlorobenzylthio)-3-(4-fluoro-3-nitrop...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326068((E)-3-(4-Fluoro-3-nitrophenyl)-2-(4-fluorobenzylth...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326065((E)-4-(2-(4-Fluorobenzylthio)-3-(4-chloro-3-nitrop...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50326061((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ErbB2 by immunoprecipitation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326059((E)-4-(2-(4-Bromobenzylthio)-3-(4-chloro-3-nitroph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326063((E)-4-(2-(4-Chlorobenzylthio)-3-(4-chloro-3-nitrop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326069((E)-4-(3-(4-Chloro-3-nitrophenyl)-2-(2-fluorobenzy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326070((E)-4-(2-(2-Chlorobenzylthio)-3-(4-fluoro-3-nitrop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326060((E)-4-(2-(4-Bromobenzylthio)-3-(4-bromo-3-nitrophe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50326061((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of GST-tagged recombinant Src after 20 mins by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326067((E)-4-(2-(4-Fluorobenzylthio)-3-(4-bromo-3-nitroph...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50326061((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of GST-tagged recombinant LynB after 20 mins by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326083((E)-4-(2-(4-Bromobenzylthio)-3-(4-hydroxy-3-bromo)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326085((E)-4-(2-(4-Bromobenzylthio)-3-(2-fluoro-5-nitroph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50326061((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EGFR by immunoprecipitation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326086((E)-4-(2-(4-Bromobenzylthio)-3-(3-fluoro-4-nitroph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326088((E)-4-(2-(4-Bromobenzylthio)-3-(2-fluoro-4-nitroph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326082((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-methoxy...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326084((E)-4-(2-(4-Bromobenzylthio)-3-(4-hydroxy-3-nitrop...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326079((E)-4-(2-(4-Bromobenzylsulfonyl)-3-(4-fluoro-3-nit...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326087((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-2-nitroph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326080((E)-4-(2-(4-Bromobenzylsulfonyl)-3-(4-chloro-3-nit...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326078((E)-4-(2-(4-Bromobenzylsulfinyl)-3-(4-fluoro-3-nit...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
LigandPNGBDBM50326081((E)-4-(2-(4-Bromophenylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50326061((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GST-tagged recombinant CDK1 after 20 mins by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50326061((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GST-tagged recombinant PLK1 after 20 mins by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed