Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50031149
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50107130((Z)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)
Affinity DataKd:  4.40E+4nMAssay Description:Displacement of fluorescein-labeled Bak-BH3 peptide from human Mcl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50107130((Z)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)
Affinity DataKd:  8.40E+4nMAssay Description:Binding affinity to human Mcl1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50308110((S,Z)-2-(5-((6-(2,3-dimethoxyphenyl)pyridin-3-yl)m...)
Affinity DataKd:  6.90E+3nMAssay Description:Displacement of fluorescein-labeled Bak-BH3 peptide from human Mcl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50308110((S,Z)-2-(5-((6-(2,3-dimethoxyphenyl)pyridin-3-yl)m...)
Affinity DataKd:  250nMAssay Description:Binding affinity to human Mcl1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50308111((S,Z)-2-(5-((6-(3,4-dimethoxyphenyl)pyridin-3-yl)m...)
Affinity DataKd:  8.00E+3nMAssay Description:Displacement of fluorescein-labeled Bak-BH3 peptide from human Mcl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50308111((S,Z)-2-(5-((6-(3,4-dimethoxyphenyl)pyridin-3-yl)m...)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to human Mcl1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50308110((S,Z)-2-(5-((6-(2,3-dimethoxyphenyl)pyridin-3-yl)m...)
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity to human Bcl-XL by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50308110((S,Z)-2-(5-((6-(2,3-dimethoxyphenyl)pyridin-3-yl)m...)
Affinity DataKi:  3.70E+3nMAssay Description:Displacement of fluorescein-labeled Bak-BH3 peptide from human Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50107130((Z)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)
Affinity DataKi:  8.70E+3nMAssay Description:Binding affinity to human Bcl-XL by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50107130((Z)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of fluorescein-labeled Bak-BH3 peptide from human Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50308111((S,Z)-2-(5-((6-(3,4-dimethoxyphenyl)pyridin-3-yl)m...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein-labeled Bak-BH3 peptide from human Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Institute of Chemical and Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50308111((S,Z)-2-(5-((6-(3,4-dimethoxyphenyl)pyridin-3-yl)m...)
Affinity DataKi: >7.50E+5nMAssay Description:Binding affinity to human Bcl-XL by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed