Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50039106
LigandPNGBDBM50366567(ATOMOXETINE)
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50313549(CHEMBL1085197 | CHEMBL1204411 | {3-[1-(2-Fluoro-ph...)
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313550(CHEMBL1085198 | CHEMBL1204412 | {3-[1-(2,6-Difluor...)
Affinity DataIC50: 5nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313552(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313548(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)
Affinity DataIC50: 12nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313553(CHEMBL1099373 | CHEMBL1204415 | {3-[1-(2,6-Difluor...)
Affinity DataIC50: 25nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313551(CHEMBL1095367 | CHEMBL1204413 | [3-(6-Fluoro-2,2-d...)
Affinity DataIC50: 26nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313553(CHEMBL1099373 | CHEMBL1204415 | {3-[1-(2,6-Difluor...)
Affinity DataIC50: 27nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313543({3-[1-(2-Fluoro-phenyl)-2,2-dioxo-1,4-dihydro-2H-2...)
Affinity DataIC50: 29nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313547({4-[6-Fluoro-1-(2-fluoro-phenyl)-2,2-dioxo-1,4-dih...)
Affinity DataIC50: 30nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313544({4-[1-(2-Fluoro-phenyl)-2,2-dioxo-1,4-dihydro-2H-2...)
Affinity DataIC50: 38nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313550(CHEMBL1085198 | CHEMBL1204412 | {3-[1-(2,6-Difluor...)
Affinity DataIC50: 52nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313549(CHEMBL1085197 | CHEMBL1204411 | {3-[1-(2-Fluoro-ph...)
Affinity DataIC50: 55nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313548(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)
Affinity DataIC50: 88nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313552(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)
Affinity DataIC50: 93nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313547({4-[6-Fluoro-1-(2-fluoro-phenyl)-2,2-dioxo-1,4-dih...)
Affinity DataIC50: 110nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313546({3-[6-Fluoro-1-(2-fluoro-phenyl)-2,2-dioxo-1,4-dih...)
Affinity DataIC50: 120nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313532([3-(2,2-Dioxo-1-phenyl-1,4-dihydro-2H-2lambda*6*-b...)
Affinity DataIC50: 130nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313537([3-(2,2-Dioxo-1-p-tolyl-1,4-dihydro-2lambda*6*-ben...)
Affinity DataIC50: 140nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313551(CHEMBL1095367 | CHEMBL1204413 | [3-(6-Fluoro-2,2-d...)
Affinity DataIC50: 170nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313542({2-[1-(2-Fluoro-phenyl)-2,2-dioxo-1,4-dihydro-2H-2...)
Affinity DataIC50: 200nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313551(CHEMBL1095367 | CHEMBL1204413 | [3-(6-Fluoro-2,2-d...)
Affinity DataIC50: 240nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313552(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)
Affinity DataIC50: 340nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313536({3-[1-(4-Fluoro-phenyl)-2,2-dioxo-1,4-dihydro-2H-2...)
Affinity DataIC50: 490nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313553(CHEMBL1099373 | CHEMBL1204415 | {3-[1-(2,6-Difluor...)
Affinity DataIC50: 600nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313533({3-[1-(3-Fluoro-phenyl)-2,2-dioxo-1,4-dihydro-2H-2...)
Affinity DataIC50: 630nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313552(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)
Affinity DataIC50: 720nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313535({3-[1-(3-Methoxy-phenyl)-2,2-dioxo-1,4-dihydro-2H-...)
Affinity DataIC50: 790nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313539({3-[1-(4-Chloro-phenyl)-2,2-dioxo-1,4-dihydro-2H-2...)
Affinity DataIC50: 910nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313540({3-[1-(3,4-Difluoro-phenyl)-2,2-dioxo-1,4-dihydro-...)
Affinity DataIC50: 970nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313534([3-(2,2-Dioxo-1-m-tolyl-1,4-dihydro-2H-2lambda*6*-...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313545({2-[6-Fluoro-1-(2-fluoro-phenyl)-2,2-dioxo-1,4-dih...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313546({3-[6-Fluoro-1-(2-fluoro-phenyl)-2,2-dioxo-1,4-dih...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313541({3-[1-(3-Chloro-4-fluoro-phenyl)-2,2-dioxo-1,4-dih...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313544({4-[1-(2-Fluoro-phenyl)-2,2-dioxo-1,4-dihydro-2H-2...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313548(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50313538({3-[1-(4-Methoxy-phenyl)-2,2-dioxo-1,4-dihydro-2H-...)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313551(CHEMBL1095367 | CHEMBL1204413 | [3-(6-Fluoro-2,2-d...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [3H]WIN-35428 from human recombinant DAT expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313543({3-[1-(2-Fluoro-phenyl)-2,2-dioxo-1,4-dihydro-2H-2...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313532([3-(2,2-Dioxo-1-phenyl-1,4-dihydro-2H-2lambda*6*-b...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313548(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)
Affinity DataIC50: 6.60E+3nMAssay Description:Displacement of [3H]WIN-35428 from human recombinant DAT expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313548(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313550(CHEMBL1085198 | CHEMBL1204412 | {3-[1-(2,6-Difluor...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50313545({2-[6-Fluoro-1-(2-fluoro-phenyl)-2,2-dioxo-1,4-dih...)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed