Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50031116
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307380(N-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl-2-methyl-pr...)
Affinity DataKi: <1nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307379(N-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl-2-methyl-pr...)
Affinity DataKi:  9nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307385(N-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl-2-methyl-pr...)
Affinity DataKi:  60nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307381(N-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl-2-methyl-pr...)
Affinity DataKi:  75nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307384(N-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl-2-methyl-pr...)
Affinity DataKi:  80nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307374(N-[(1S,2S,4R)-1-(3,5-difluorophenoxymethyl)-4-(4-f...)
Affinity DataKi:  100nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307375(N-[(1S,2S,4R)-1-(3,5-difluorophenoxymethyl)-2-hydr...)
Affinity DataKi:  200nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307382(N-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl-2-methyl-pr...)
Affinity DataKi:  220nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307377(N-[(1S,2S,4R)-1-(3,5-Difluorophenoxymethyl)-2-hydr...)
Affinity DataKi:  400nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307379(N-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl-2-methyl-pr...)
Affinity DataKi:  460nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307381(N-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl-2-methyl-pr...)
Affinity DataKi:  840nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307380(N-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl-2-methyl-pr...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307376(N-[(1S,2S,4R)-4-Benzylcarbamoyl-1-(3,5-difluorophe...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307378(N-[(1S,2S,4R)-4-Cyclopropylcarbamoyl-1-(3,5-difluo...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307375(N-[(1S,2S,4R)-1-(3,5-difluorophenoxymethyl)-2-hydr...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307376(N-[(1S,2S,4R)-4-Benzylcarbamoyl-1-(3,5-difluorophe...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307377(N-[(1S,2S,4R)-1-(3,5-Difluorophenoxymethyl)-2-hydr...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307378(N-[(1S,2S,4R)-4-Cyclopropylcarbamoyl-1-(3,5-difluo...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCathepsin D(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307374(N-[(1S,2S,4R)-1-(3,5-difluorophenoxymethyl)-4-(4-f...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50307383(N-[(1S,2S,4R)-4-((S)-1-Benzylcarbamoyl-2-methyl-pr...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli cells (BL21(DE3) by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed