Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50031400
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312651(RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312652(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312663(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  6.80nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312658(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  11nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312662(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  12nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312654(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  13nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312656(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  15nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312664(1-{N-[2-(Amidino-N0-methylaminooxy)ethyl]amino}car...)
Affinity DataKi:  37nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312661(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  44nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312657(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  47nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312655(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  47nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312660(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  66nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312659(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  120nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312651(RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of tissue-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312651(RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312652(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312651(RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312652(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312652(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCathepsin G(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312652(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312652(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetChymase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312652(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312652(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312651(RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetChymase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCathepsin G(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCathepsin G(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312651(RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312651(RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312651(RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPlasminogen(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetChymase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312651(RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed