Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50031491
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200841(CHEMBL220360 | N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314119(3-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-pivaloy...)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314122(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-isobuty...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314118(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-pivaloy...)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314121(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-pivaloy...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314120(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-pivaloy...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314113(1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)fu...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259339(5-tert-butyl-8-(2-chlorophenyl)-9-(4-chlorophenyl)...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314112(1-(3-amino-5-(4-chlorophenyl)-6-(2,4-dichloropheny...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314114((3-amino-5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314116(1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)fu...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314123(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314115(1-(3-amino-5-(4-chlorophenyl)-6-(2,4-dichloropheny...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259140(2-tert-butyl-6-(4-chlorophenyl)-7-(2,4-dichlorophe...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50176435(N-(3-acetyl-6-(4-chlorophenyl)-7-(2,4-dichlorophen...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314111(1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)fu...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314110(1-(3-amino-5-(4-chlorophenyl)-6-(2,4-dichloropheny...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314117(1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)fu...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314109(1-(3-amino-5-(4-chlorophenyl)-6-(2,4-dichloropheny...)
Affinity DataIC50: 56nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314110(1-(3-amino-5-(4-chlorophenyl)-6-(2,4-dichloropheny...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314114((3-amino-5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314115(1-(3-amino-5-(4-chlorophenyl)-6-(2,4-dichloropheny...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314112(1-(3-amino-5-(4-chlorophenyl)-6-(2,4-dichloropheny...)
Affinity DataIC50: 640nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314111(1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)fu...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314109(1-(3-amino-5-(4-chlorophenyl)-6-(2,4-dichloropheny...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314113(1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)fu...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314116(1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)fu...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314119(3-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-pivaloy...)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314118(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-pivaloy...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314117(1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)fu...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314120(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-pivaloy...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314121(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-pivaloy...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314122(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-isobuty...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314123(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human ERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314108(N-(6-(2-chlorophenyl)-5-(4-chlorophenyl)-2-(2-hydr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed